D-SNAP
Based on 1 Customer Validation
D-SNAP (S-Nitroso-N-acetylpenicillamine) can Generate nitric oxide and form superoxides spontaneously under physiological conditions and is often used to probe the cell stress response and stimulate calcium-independent synaptic vesicle release.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 95.0%
- CAS 番号: 79032-48-7
- 分子式: C7H12N2O4S
- 分子量:220.25
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保管条件:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
生物活性
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HT-29 | EC50 |
>1000 μM
Compound: SNAP
|
Apoptosis induction in human HT29 cells after 24 hrs
Apoptosis induction in human HT29 cells after 24 hrs
|
[PMID: 17441704] |
| LLC-MK2 | CC50 |
200 μM
Compound: SNAP
|
Cytotoxicity against monkey LLC-MK2 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
Cytotoxicity against monkey LLC-MK2 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
|
[PMID: 37159959] |
化学情報
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CAS 番号 79032-48-7
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性状 Solid
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分子量 220.25
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分子式 C7H12N2O4S
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Color Light green to green
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SMILES
O=NSC(C)(C)[C@H](C(O)=O)NC(C)=O
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別名
S-Nitroso-N-acetylpenicillamine
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
溶剤 & 溶解度
DMSO : ≥ 100 mg/mL (454.03 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (244 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.5403 mL | 22.7015 mL | 45.4030 mL | 113.5074 mL |
| 5 mM | 0.9081 mL | 4.5403 mL | 9.0806 mL | 22.7015 mL | |
| 10 mM | 0.4540 mL | 2.2701 mL | 4.5403 mL | 11.3507 mL | |
| 15 mM | 0.3027 mL | 1.5134 mL | 3.0269 mL | 7.5672 mL | |
| 20 mM | 0.2270 mL | 1.1351 mL | 2.2701 mL | 5.6754 mL | |
| 25 mM | 0.1816 mL | 0.9081 mL | 1.8161 mL | 4.5403 mL | |
| 30 mM | 0.1513 mL | 0.7567 mL | 1.5134 mL | 3.7836 mL | |
| 40 mM | 0.1135 mL | 0.5675 mL | 1.1351 mL | 2.8377 mL | |
| 50 mM | 0.0908 mL | 0.4540 mL | 0.9081 mL | 2.2701 mL | |
| 60 mM | 0.0757 mL | 0.3784 mL | 0.7567 mL | 1.8918 mL | |
| 80 mM | 0.0568 mL | 0.2838 mL | 0.5675 mL | 1.4188 mL | |
| 100 mM | 0.0454 mL | 0.2270 mL | 0.4540 mL | 1.1351 mL |