DA 1686
DA 1686 is an orally active naphthalene derivative that induces bradycardia and mild hypotension. DA 1686 can be used in the study of arrhythmias.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 13071-27-7
- 分子式: C23H32N2O2
- 分子量:368.51
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
DA 1686 reduces aconitine-induced tachycardia and responsiveness to increased electrical stimulation in isolated guinea-pig auricles[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
DA 1686 (20 mg/kg; i.v.; slow infusion) protects anaesthetized dogs from Adrenaline (HY-B0447)-induced death during benzol inhalation[1].
DA 1686 protects rats from arrhythmia induced by intravenous administration of 34 μg/kg Aconitine[1].
DA 1686 delays the onset of Ouabain (HY-B1457)-induced arrhythmia, ventricular fibrillation, and cardiac arrest in guinea-pigs[1].
DA 1686 reduces tachycardia induced by 10 days of daily 0.2 mg Thyroxine (HY-18341) administration in rabbits[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Dog[1]
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Dosage:20 mg/kg
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Administration:i.v.; slow infusion
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Result:Protected anaesthetized dogs from death induced by rapid intravenous adrenaline administration during benzol inhalation.
化学情報
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CAS 番号 13071-27-7
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分子量 368.51
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分子式 C23H32N2O2
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SMILES
N1(CCC(CCN2CCOCC2)C3=CC=CC4=C3C=CC=C4)CCOCC1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)