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United States

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製品番号: HY-N7589

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Demethylcarolignan E

(別名: Carolignan M)

Demethylcarolignan E is a phenylpropanoid ester that can be isolated from the stems of Hibiscus taiwanensi. Demethylcarolignan E has cytotoxicity against human cancer lines A549 and MCF-7 (IC₅₀: <10 μg/mL).

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研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 873694-46-3
分子式: C₃₉H₄₀O₁₃
分子量:716.73

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

Demethylcarolignan E 構造式

CAS 番号: 873694-46-3

容量

価格（税別）

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数量

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Cellular Effect

Cell Line	Type	Value	Description	References
DLD-1	IC₅₀	>40 μM Compound: 2	Cytotoxicity against human Wnt-dependent DLD1 cells after 24 hrs by fluorometric microculture cytotoxicity assay Cytotoxicity against human Wnt-dependent DLD1 cells after 24 hrs by fluorometric microculture cytotoxicity assay	[PMID: 26026364]
HCT-116	IC₅₀	>39 μM Compound: 2	Cytotoxicity against human Wnt-dependent HCT116 cells after 24 hrs by fluorometric microculture cytotoxicity assay Cytotoxicity against human Wnt-dependent HCT116 cells after 24 hrs by fluorometric microculture cytotoxicity assay	[PMID: 26026364]
HEK293	IC₅₀	24.2 μM Compound: 2	Cytotoxicity against human HEK293 cells after 24 hrs by fluorometric microculture cytotoxicity assay Cytotoxicity against human HEK293 cells after 24 hrs by fluorometric microculture cytotoxicity assay	[PMID: 26026364]
HEK293	IC₅₀	4.5 μM Compound: 2	Inhibition of Wnt/beta-catenin signaling in HEK293 cells stably transfected with TOP reporter gene assessed as TCF/beta-catenin transcriptional activity after 24 hrs by TOP activity/luciferase reporter gene assay Inhibition of Wnt/beta-catenin signaling in HEK293 cells stably transfected with TOP reporter gene assessed as TCF/beta-catenin transcriptional activity after 24 hrs by TOP activity/luciferase reporter gene assay	[PMID: 26026364]
RKO	IC₅₀	23 μM Compound: 2	Cytotoxicity against human Wnt-independent RKO cells after 24 hrs by fluorometric microculture cytotoxicity assay Cytotoxicity against human Wnt-independent RKO cells after 24 hrs by fluorometric microculture cytotoxicity assay	[PMID: 26026364]
SW480	IC₅₀	>40 μM Compound: 2	Cytotoxicity against human Wnt-dependent SW480 cells after 24 hrs by fluorometric microculture cytotoxicity assay Cytotoxicity against human Wnt-dependent SW480 cells after 24 hrs by fluorometric microculture cytotoxicity assay	[PMID: 26026364]

化学情報

CAS 番号 873694-46-3
分子量 716.73
分子式 C₃₉H₄₀O₁₃
SMILES

O=C(OC[C@H](OC1=CC=C(CCCOC(/C=C/C2=CC=C(O)C(OC)=C2)=O)C=C1O)[C@@H](O)C3=CC=C(O)C(OC)=C3)/C=C/C4=CC=C(O)C(OC)=C4
別名

Carolignan M
Structure Classification
- Phenols
- Polyphenols
Initial Source
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (266 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Wu PL, et al. Cytotoxicity of phenylpropanoid esters from the stems of Hibiscus taiwanensis. Bioorg Med Chem. 2004 May 1;12(9):2193-7. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

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分子量分子量

希釈計算機

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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