DL-AP4 (Standard)
DL-AP4 (Standard) is the analytical standard of DL-AP4. This product is intended for research and analytical applications. DL-AP4 (2-Amino-4-phosphonobutyric acid) is a glutamate antagonist. DL-AP4 behaves as a competitive inhibitor of glutamate binding with an apparent Kd of 66 μM. DL-AP4 can be used for the research of central nervous system and visual system.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 6323-99-5
- 分子式: C4H10NO5P
- 分子量:183.10
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
化学情報
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CAS 番号 6323-99-5
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分子量 183.10
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分子式 C4H10NO5P
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SMILES
O=C(O)C(N)CCP(O)(O)=O
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別名
2-Amino-4-phosphonobutyric acid (Standard)
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Cull-Candy SG, et al. 2-Amino-4-phosphonobutyric acid as a glutamate antagonist on locust muscle. Nature. 1976 Jul 29;262(5567):408-9. [Content Brief]
[2]. Yamashita M, et al. Responses of rod bipolar cells isolated from the rat retina to the glutamate agonist 2-amino-4-phosphonobutyric acid (APB). J Neurosci. 1991 Aug;11(8):2372-82. [Content Brief]
[3]. Crooks SL, et al. Cyclic analogues of 2-amino-4-phosphonobutanoic acid (APB) and their inhibition of hippocampal excitatory transmission and displacement of [3H]APB binding. J Med Chem. 1986 Oct;29(10):1988-95. [Content Brief]
[4]. Ellis EM, et al. Separate ON and OFF pathways in vertebrate vision first arose during the Cambrian. Curr Biol. 2020 Jun 8;30(11):R633-R634. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)