Flubeneteram
Flubeneteram is a succinate dehydrogenase inhibitor with an IC50 of 0.0484 μM. Flubeneteram disrupts succinate dehydrogenase activity. Flubeneteram demonstrates protective effects against Rhizoctonia solani and Sphaerotheca fuliginea in preclinical models. Flubeneteram can be used for research related to fungal infections.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1676101-39-5
- 分子式: C19H13ClF5N3O2
- 分子量:445.77
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
体外実験
Flubeneteram (0.01-50 μM) potently inhibits succinate dehydrogenase in a in vitro cell-free assay with an IC50 of 0.0484 μM[1].
Flubeneteram (0.75-200 mg/L) exhibits 100% control of both rice sheath blight (caused by Rhizoctonia solani) and cucumber powdery mildew (caused by Sphaerotheca fuliginea) at concentrations of 200, 100, and 50 mg/L, with potent activity maintained at lower concentrations against rice sheath blight[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
化学情報
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CAS 番号 1676101-39-5
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分子量 445.77
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分子式 C19H13ClF5N3O2
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SMILES
O=C(C1=CN(C)N=C1C(F)F)NC2=C(OC3=CC=C(C(F)(F)F)C=C3Cl)C=CC=C2
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
プロトコル
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)