CDC20B - cell division cycle 20B Gene

Also Known as G6VTS76519

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 166979

About CDC20B

This gene has 5 transcripts (splice variants), 121 orthologues and 2 paralogues. Low expression observed in reference dataset.

Summary

Predicted to enable anaphase-promoting complex binding activity and ubiquitin Ligase activator activity. Predicted to be involved in anaphase-promoting complex-dependent catabolic process and positive regulation of anaphase-promoting complex-dependent catabolic process. Predicted to be part of anaphase-promoting complex. [provided by Alliance of Genome Resources, Apr 2022]

CDC20B Products (3)

mRNA Protein Name
NM_001145734.2 NP_001139206.2 cell division cycle protein 20 homolog B isoform 2
NM_001170402.1 NP_001163873.1 cell division cycle protein 20 homolog B isoform 3
NM_152623.2 NP_689836.2 cell division cycle protein 20 homolog B isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence 参考文献 由来
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
Biological Process GO Annotation Evidence 参考文献 由来
involved in de novo centriole assembly IDA
IDA: Inferred from direct assay
30405130 GOA
Cellular Component GO Annotation Evidence 参考文献 由来
located in deuterosome IDA
IDA: Inferred from direct assay
30405130 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CDC20B Protein Structure

WD40

WD40: WD domain, G-beta repeat (354 - 382)

WD40

WD40: WD domain, G-beta repeat (485 - 517)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 519 a.a.
Protein Preferred Names Protein Names

cell division cycle protein 20 homolog B

  • CDC20 cell division cycle 20 homolog B

CDC20B Protein-protein interaction Information

Type
タンパク質名 Protein ID Interactor Interactor Species Interactor ID Detection Method 参考文献
Intra
CDC20B Q86Y33 KRT40 Homo sapiens Q6A162
Validated Y2H
25416956
Intra
CDC20B Q86Y33 KRT40 Homo sapiens Q6A162
Y2H Array
25416956
Intra
CDC20B Q86Y33 MAGEA11 Homo sapiens P43364-2
Y2H Array
25416956
Intra
CDC20B Q86Y33 CCDC57 Homo sapiens Q2TAC2
Y2H Prey Pooling
25416956
Intra
CDC20B Q86Y33 CCDC57 Homo sapiens Q2TAC2
Validated Y2H
25416956
Intra
CDC20B Q86Y33 CCDC57 Homo sapiens Q2TAC2
Y2H Array
25416956
Intra
CDC20B Q86Y33 TRAF2 Homo sapiens Q12933
Validated Y2H
25416956
Intra
CDC20B Q86Y33 TRAF2 Homo sapiens Q12933
Y2H Array
25416956
Intra
CDC20B Q86Y33 SPAG5 Homo sapiens Q96R06
Validated Y2H
25416956
Intra
CDC20B Q86Y33 GOLGA2 Homo sapiens Q08379
Y2H Array
25416956
Intra
CDC20B Q86Y33 GOLGA2 Homo sapiens Q08379
Validated Y2H
25416956
Intra
CDC20B Q86Y33 TRIM27 Homo sapiens P14373
Y2H Array
25416956
Intra
CDC20B Q86Y33 TRIM27 Homo sapiens P14373
Validated Y2H
25416956
Intra
CDC20B Q86Y33 PLK2 Homo sapiens Q9NYY3
Validated Y2H
25416956
Intra
CDC20B Q86Y33 PLK2 Homo sapiens Q9NYY3
Y2H Array
25416956
Intra
CDC20B Q86Y33 PLK2 Homo sapiens Q9NYY3
Y2H Prey Pooling
25416956
Intra
CDC20B Q86Y33 TRIM23 Homo sapiens P36406
Y2H Prey Pooling
25416956
Intra
CDC20B Q86Y33 TRIM23 Homo sapiens P36406
Y2H Array
25416956
Intra
CDC20B Q86Y33 TRIM37 Homo sapiens O94972
Y2H Array
25416956
Intra
CDC20B Q86Y33 TRIM37 Homo sapiens O94972
Y2H Prey Pooling
25416956
Intra
CDC20B Q86Y33 MTUS2 Homo sapiens Q5JR59
Y2H Prey Pooling
25416956
Intra
CDC20B Q86Y33 MTUS2 Homo sapiens Q5JR59
Validated Y2H
25416956
Intra
CDC20B Q86Y33 KRT31 Homo sapiens Q15323
Validated Y2H
25416956
Intra
CDC20B Q86Y33 KRT31 Homo sapiens Q15323
Y2H Array
25416956
Intra
CDC20B Q86Y33 KRT31 Homo sapiens Q15323
Y2H Prey Pooling
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS02289 CDC20B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Macaca mulatta CDC20B VGNC VGNC:70843
Felis catus CDC20B VGNC VGNC:102177
Bos taurus CDC20B VGNC VGNC:27061
Mus musculus CDC20B MGD MGI:3644472
Canis familiaris CDC20B VGNC VGNC:38988
Rattus norvegicus CDC20B RGD RGD:1584143
Others CDC20B NCBI