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GNE-783

GNE-783 is a selective CHK1 inhibitor that enhances the activity of gemcitabine. GNE-783 improves the efficacy of anti-metabolite DNA damage drugs by inactivating S-phase and G2-phase cell cycle checkpoints following DNA damage. GNE-783 selectively enhances the chemical synergy of certain drugs in different tumor types, for example, enhancing the activity of temozolomide only in melanoma cell lines.

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  • CAS 番号: 1200127-66-7
  • 分子式: C22H20N6
  • 分子量:368.43
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • GNE-783 Chemical Structure
    GNE-783 構造式
CAS 番号: 1200127-66-7
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  • GNE-783 Chemical Structure
    GNE-783 Chemical Structure
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  • GNE-783