Tyk2-IN-14
Tyk2-IN-14 is a Tyk2 inhibitor that regulates IFNα and IL-23 by inhibiting Tyk2-mediated signal transduction. Tyk2-IN-14 exhibits an IC50 of 0.08 μM against the IL-23 Kit225 reporter gene and an IC50 of 0.09 μM against the IFNα Kit225 reporter gene. IL-23 modulator-1 is applicable to the research of inflammatory diseases and autoimmune diseases.
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- CAS 番号: 1609392-06-4
- 分子式: C18H18N6O3S
- 分子量:398.44
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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Tyk2 |
IL-23 0.08 μM (IC50) |
Tyk2-IN-14 (CPD31) inhibits IL-23-induced reporter gene activity in Kit225 T cells with an IC50 of 0.08 μM; it also inhibits IFNα-induced reporter gene activity in Kit225 T cells with an IC50 of 0.09 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1609392-06-4
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分子量 398.44
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分子式 C18H18N6O3S
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SMILES
O=C(NC)C1=NN=C(C=C1NC=2C=CC=CC2S(=O)(=O)C)NC3=NC=CC=C3
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Tyk2-IN-14 関連分類
HY-184786 関連分類
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