country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

製品番号: HY-182692

Copy Link Print Information

KMO-IN-1

KMO-IN-1 is a KMO inhibitor with a mean pIC₅₀ of 8.5 against KMO. KMO-IN-1 can be used in the research of acute pancreatitis.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 1953156-92-7
分子式: C₁₈H₁₇ClN₂O₄
分子量:360.79

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

KMO-IN-1 構造式

CAS 番号: 1953156-92-7

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

KMO-IN-1 is a KMO inhibitor with a mean pIC₅₀ of 8.5 against KMO. KMO-IN-1 can be used in the research of acute pancreatitis^[1].

体外実験

KMO-IN-1 (Compound 30) potently inhibits human KMO with a mean pIC₅₀ of 8.5^[1].
KMO-IN-1 potently inhibits KMO activity in HEK cells with a mean pIC₅₀ of 8.8^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .

Parmacokinetics

Species	Dose	Route	T_1/2	CL_blood	V_dss
Rat^[1]	1 mg/kg	i.v.	3.6 h	1.1 mL/min/kg	0.31 L/kg

化学情報

CAS 番号 1953156-92-7
分子量 360.79
分子式 C₁₈H₁₇ClN₂O₄
SMILES

OC(CCC(C1=C2)=NOC1=CC(O[C@@H](C3=CC=C(C=N3)C)C)=C2Cl)=O
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Walker AL, et al. Development of a Series of Kynurenine 3-Monooxygenase Inhibitors Leading to a Clinical Candidate for the Treatment of Acute Pancreatitis. J Med Chem. 2017;60(8):3383-3404. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

お問い合わせ在庫あり

Other size

お問い合わせ