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United States

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製品番号: HY-117746

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KSK120

KSK120 is a potent inhibitor of drug-resistant infections with specific activity against Chlamydia trachomatis (C. trachomatis). KSK120 inhibits the developmental cycle of C. trachomatis, thereby reducing the infectivity of progeny bacteria. KSK120 targets the glucose-6-phosphate (G-6P) metabolic pathway of C. trachomatis, showing its potential application in antimicrobial inhibition. The mechanism of KSK120 may involve inhibition of the transcriptional machinery, which provides new ideas for the development of specific drugs against C. trachomatis infection.

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CAS 番号: 1638100-63-6
分子式: C₂₈H₂₂N₂O₂S
分子量:450.55

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

KSK120 構造式

CAS 番号: 1638100-63-6

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Cellular Effect

Cell Line	Type	Value	Description	References
HeLa	EC₅₀	1.25 μM Compound: 1; KSK 120	Antimicrobial activity against Chlamydia trachomatis serovar LGV-L2 infected in human HeLa cells measured 44 to 48 hrs post infection by DAPI staining-based assay Antimicrobial activity against Chlamydia trachomatis serovar LGV-L2 infected in human HeLa cells measured 44 to 48 hrs post infection by DAPI staining-based assay	[PMID: 26849778]
HeLa	EC₅₀	254 nM Compound: 1; KSK 120	Antimicrobial activity against Chlamydia trachomatis serovar LGV-L2 infected in human HeLa cells assessed as decrease in relative inclusion forming units measured 44 to 48 hrs post infection by DAPI staining-based assay Antimicrobial activity against Chlamydia trachomatis serovar LGV-L2 infected in human HeLa cells assessed as decrease in relative inclusion forming units measured 44 to 48 hrs post infection by DAPI staining-based assay	[PMID: 26849778]

化学情報

CAS 番号 1638100-63-6
分子量 450.55
分子式 C₂₈H₂₂N₂O₂S
SMILES

O=C(C=C1CC2=CC=CC3=C2C=CC=C3)N4C(C(NC5=CC=CC=C5)=O)=CSC4=C1C6CC6
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (269 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. A 2-pyridone amide inhibitor of transcriptional activity in Chlamydia trachomatis

Calculators

モル濃度計算機

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分子量分子量

希釈計算機

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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