Mannose 1-phosphate
Mannose 1-phosphate is a phosphorylated mannose that serves as a precursor of GDP-mannose, a constituent unit of glycosylation biosynthetic pathways. Mannose 1-phosphate increases intracellular GDP-mannose concentration, promotes normalization of lipid-linked oligosaccharide structures, and enhances the formation of mature N-glycans on cellular proteins. Mannose 1-phosphate can be used in studies related to glycosylation disorders.
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- CAS 番号: 27251-84-9
- 分子式: C6H13O9P
- 分子量:260.14
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
Endogenous Metabolite アイソフォーム固有の製品をすべて表示
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生物活性
製品説明
体外実験
Mannose 1-phosphate (1 mM; 24 h) significantly improves global N-glycosylation by increasing mature Man6+ high mannose and complex/hybrid glycopeptides, and reduces immature smaller glycans, in PMM2-CDG, ALG2-CDG, and ALG11-CDG skin fibroblasts, with the most dramatic effects observed in PMM2-CDG and ALG2-CDG cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
化学情報
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CAS 番号 27251-84-9
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分子量 260.14
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分子式 C6H13O9P
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SMILES
O[C@@H]1C(OP(O)(O)=O)O[C@H](CO)[C@@H](O)[C@@H]1O
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Mannose 1-phosphate 関連分類
HY-16304 関連分類
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