Mannose 1-phosphate sodium
Based on 1 Customer Validation
Mannose 1-phosphate sodium is a phosphorylated mannose that serves as a precursor of GDP-mannose, a constituent unit of glycosylation biosynthetic pathways. Mannose 1-phosphate sodium increases intracellular GDP-mannose concentration, promotes normalization of lipid-linked oligosaccharide structures, and enhances the formation of mature N-glycans on cellular proteins. Mannose 1-phosphate sodium can be used in studies related to glycosylation disorders.
For research use only. We do not sell to patients.
- Formula: C6H12NaO9P
- Molecular Weight:282.12
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
Mannose 1-phosphate (1 mM; 24 h) sodium significantly improves global N-glycosylation by increasing mature Man6+ high mannose and complex/hybrid glycopeptides, and reduces immature smaller glycans, in PMM2-CDG, ALG2-CDG, and ALG11-CDG skin fibroblasts, with the most dramatic effects observed in PMM2-CDG and ALG2-CDG cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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Molecular Weight 282.12
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Formula C6H12NaO9P
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SMILES
O[C@@H]1C(OP(O)(O[Na])=O)O[C@H](CO)[C@@H](O)[C@@H]1O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
H2O : 100 mg/mL (354.46 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 3.5446 mL | 17.7230 mL | 35.4459 mL | 88.6148 mL |
| 5 mM | 0.7089 mL | 3.5446 mL | 7.0892 mL | 17.7230 mL | |
| 10 mM | 0.3545 mL | 1.7723 mL | 3.5446 mL | 8.8615 mL | |
| 15 mM | 0.2363 mL | 1.1815 mL | 2.3631 mL | 5.9077 mL | |
| 20 mM | 0.1772 mL | 0.8861 mL | 1.7723 mL | 4.4307 mL | |
| 25 mM | 0.1418 mL | 0.7089 mL | 1.4178 mL | 3.5446 mL | |
| 30 mM | 0.1182 mL | 0.5908 mL | 1.1815 mL | 2.9538 mL | |
| 40 mM | 0.0886 mL | 0.4431 mL | 0.8861 mL | 2.2154 mL | |
| 50 mM | 0.0709 mL | 0.3545 mL | 0.7089 mL | 1.7723 mL | |
| 60 mM | 0.0591 mL | 0.2954 mL | 0.5908 mL | 1.4769 mL | |
| 80 mM | 0.0443 mL | 0.2215 mL | 0.4431 mL | 1.1077 mL | |
| 100 mM | 0.0354 mL | 0.1772 mL | 0.3545 mL | 0.8861 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Mannose 1-phosphate sodium Related Classifications
HY-16304A Related Classifications
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