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製品番号: HY-N22058

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Nimonol

Name: Nimonol
Brand: MedChemExpress
SKU: HY-N22058
Availability: PreOrder

(別名: Nimocinol)

Nimonol (Nimocinol) is a tetranortriterpenoid limonoid present in the leaves of Azadirachta indica, and it undergoes photolysis to generate Nimonolide. Nimonol interferes with insect growth processes, exerts antifeedant and insecticidal effects, and exhibits insecticidal toxicity against the fourth-instar larvae of Aedes aegypti. Nimonol is used in research related to pest control.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 95260-96-1
分子式: C₂₈H₃₆O₅
分子量:452.58

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Nimonol 構造式

CAS 番号: 95260-96-1

容量

価格（税別）

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

体外実験

Fungal InfectionOthers

Fungal Infection

Nimonol exhibits no antifungal activity against Aspergillus flavus, Aspergillus fumigatus, Aspergillus niger, Aspergillus terreus, Candida albicans, or Microsporum gypseum^[2].

Others

Nimonol undergoes photooxidation in benzene under UV light and oxygen, yielding Nimocinolide as the only detectable butenolide product^[3].
When Nimonol is exposed to UV light, it produces new photoproducts, among which photoproduct 4 Nimonolide exhibits antifeedant activity against Spodoptera litura^[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

体内実験

Nimonol (Nimocinol) (41.40-82.80 ppm; in water; 24 h) exhibits larvicidal toxicity against fourth-instar Aedes aegypti larvae with an LC₅₀ of 83 ppm^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

Aedes aegypti larvae (P.C.S.I.R. strain)^[1]
Dosage:

41.40, 51.75, 62.10, 72.45, 82.80 ppm
Administration:

in water; 24 h
Result:

Produced 8% mean mortality at 41.40 ppm.
Produced 14% mean mortality at 51.75 ppm.
Produced 28% mean mortality at 62.10 ppm.
Produced 44% mean mortality at 72.45 ppm.
Produced 54% mean mortality at 82.80 ppm.
Exhibited an LC5₀ of 83 ppm.

化学情報

CAS 番号 95260-96-1
分子量 452.58
分子式 C₂₈H₃₆O₅
SMILES

C[C@]12[C@@](CC[C@@]3(C2=CC[C@H]3C4=COC=C4)C)([H])[C@@]5([C@@](C(C)(C(C=C5)=O)C)([H])[C@H]([C@H]1OC(C)=O)O)C
別名

Nimocinol
Structure Classification
- Terpenoids
- Triterpenes
Initial Source
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Siddiqui BS, et al. Two insecticidal tetranortriterpenoids from Azadirachta indica. Phytochemistry. 2000 Feb;53(3):371-6.

[2]. Mahmoud DA, et al. Antifungal activity of different neem leaf extracts and the nimonol against some important human pathogens. Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]. 2011 Jul;42(3):1007-16.

[3]. alimuzzaman Siddiqui, et al. Two new insect growth regulator meliacins from Azadirachta indica A. Juss (meliaceae). J. Chem. Soc., Perkin Trans. 1. 1986;15:1021-1025.

[4]. Geetha Gopalakrishnan, et al. Photooxygenation of Nimonol, a Tetranortriterpenoid from Azadirachta indica. A. Juss. Molecules. 2002;7(2):112-118.

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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分子量分子量

希釈計算機

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濃度 _(開始) 濃度 _(開始)

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濃度 _(終了) 濃度 _(終了)

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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