NTNCB hydrochloride
Based on 1 Customer Validation
NTNCB (Compound 11) hydrochloride is a potent and selective neuropeptide Y Y5 (NPY Y5) receptor antagonist with a Ki of 8 nM against human Y5.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 98.36%
- CAS 番号: 191931-56-3
- 分子式: C25H34ClN3O4S
- 分子量:508.07
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保管条件:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Neuropeptide Y Receptor アイソフォーム固有の製品をすべて表示
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生物活性
製品説明
IC50 & Target
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hY5 receptor 8 nM (Ki) |
hY1 receptor 16032 nM (Ki) |
化学情報
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CAS 番号 191931-56-3
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性状 Solid
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分子量 508.07
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分子式 C25H34ClN3O4S
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Color Off-white to light yellow
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SMILES
O=S(C1=CC=CC=C1[N+]([O-])=O)(NC[C@H]2CC[C@H](CNCC3CC4=C(C=CC=C4)CC3)CC2)=O.[H]Cl
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
体外:
DMSO : 125 mg/mL (246.03 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.9682 mL | 9.8412 mL | 19.6823 mL | 49.2058 mL |
| 5 mM | 0.3936 mL | 1.9682 mL | 3.9365 mL | 9.8412 mL | |
| 10 mM | 0.1968 mL | 0.9841 mL | 1.9682 mL | 4.9206 mL | |
| 15 mM | 0.1312 mL | 0.6561 mL | 1.3122 mL | 3.2804 mL | |
| 20 mM | 0.0984 mL | 0.4921 mL | 0.9841 mL | 2.4603 mL | |
| 25 mM | 0.0787 mL | 0.3936 mL | 0.7873 mL | 1.9682 mL | |
| 30 mM | 0.0656 mL | 0.3280 mL | 0.6561 mL | 1.6402 mL | |
| 40 mM | 0.0492 mL | 0.2460 mL | 0.4921 mL | 1.2301 mL | |
| 50 mM | 0.0394 mL | 0.1968 mL | 0.3936 mL | 0.9841 mL | |
| 60 mM | 0.0328 mL | 0.1640 mL | 0.3280 mL | 0.8201 mL | |
| 80 mM | 0.0246 mL | 0.1230 mL | 0.2460 mL | 0.6151 mL | |
| 100 mM | 0.0197 mL | 0.0984 mL | 0.1968 mL | 0.4921 mL |