Plumieride
Plumieride is an antifungal agent. Plumieride has strong fungitoxicity against some dermatophytes. Plumieride has little cytotoxic activity against the P388 leukaemia cell line with an IC50 of 85 μg/mL.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 511-89-7
- 分子式: C21H26O12
- 分子量:470.42
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- プロトコル
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Cancer cell lines | ED50 |
>50 μg/mL
Compound: 8
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Cytotoxicity against human breast cancer cells
Cytotoxicity against human breast cancer cells
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[PMID: 1965200] |
| Cancer cell lines | ED50 |
>50 μg/mL
Compound: 8
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Cytotoxicity against human colon cancer cells
Cytotoxicity against human colon cancer cells
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[PMID: 1965200] |
| Cancer cell lines | ED50 |
>50 μg/mL
Compound: 8
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Cytotoxicity against human lung cancer cells
Cytotoxicity against human lung cancer cells
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[PMID: 1965200] |
| HT-1080 | ED50 |
>50 μg/mL
Compound: 8
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Cytotoxicity against human HT1080 cells
Cytotoxicity against human HT1080 cells
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[PMID: 1965200] |
| KB | ED50 |
>50 μg/mL
Compound: 8
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Cytotoxicity against human KB cells
Cytotoxicity against human KB cells
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[PMID: 1965200] |
| Melanoma cell | ED50 |
>50 μg/mL
Compound: 8
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Cytotoxicity against human melanoma cells
Cytotoxicity against human melanoma cells
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[PMID: 1965200] |
| P388 | ED50 |
>50 μg/mL
Compound: 8
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Cytotoxicity against mouse P388 cells
Cytotoxicity against mouse P388 cells
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[PMID: 1965200] |
化学情報
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CAS 番号 511-89-7
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分子量 470.42
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分子式 C21H26O12
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SMILES
OC[C@H]([C@@H](O)[C@H](O)[C@H]1O)O[C@@]1([H])O[C@H]2[C@]3([H])[C@@](O4)(C=C[C@]3([H])C(C(OC)=O)=CO2)C=C([C@@H](O)C)C4=O
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別名
Agoniadin; NSC 609065
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
プロトコル
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
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Cell Viability Determination by MTT Colorimetric Assay
The following protocol uses the MTT colorimetric assay as a classic literature-established method for assessing cell viability/metabolic activity in cultured mammalian cells. MTT[3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] is reduced by metabolically active cells to a colored formazan product; the amount of formazan is quantified spectrophotometrically and provides an indirect measure of metabolically active viable cells. Importantly, MTT reduction reflects cellular oxidoreductase/metabolic activity rather than an absolute direct count of living cells, so changes in cellular metabolism can alter the signal independently of cell number.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Plumieride 関連分類
HY-N3041 関連分類
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