Propargyl-PEG4-amine
Based on 1 Customer Validation
Propargyl-PEG4-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG4-amine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.71%
- CAS 番号: 1013921-36-2
- 分子式: C11H21NO4
- 分子量:231.29
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保管条件:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
PROTAC Linkers アイソフォーム固有の製品をすべて表示
More
生物活性
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1013921-36-2
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性状 Liquid (Density: 1.037±0.06 g/cm3)
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分子量 231.29
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分子式 C11H21NO4
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Color Light yellow to brown
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SMILES
NCCOCCOCCOCCOCC#C
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別名
アミノ-PEG4-アルキン
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶剤 & 溶解度
DMSO : 50 mg/mL (216.18 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (266 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.3236 mL | 21.6179 mL | 43.2358 mL | 108.0894 mL |
| 5 mM | 0.8647 mL | 4.3236 mL | 8.6472 mL | 21.6179 mL | |
| 10 mM | 0.4324 mL | 2.1618 mL | 4.3236 mL | 10.8089 mL | |
| 15 mM | 0.2882 mL | 1.4412 mL | 2.8824 mL | 7.2060 mL | |
| 20 mM | 0.2162 mL | 1.0809 mL | 2.1618 mL | 5.4045 mL | |
| 25 mM | 0.1729 mL | 0.8647 mL | 1.7294 mL | 4.3236 mL | |
| 30 mM | 0.1441 mL | 0.7206 mL | 1.4412 mL | 3.6030 mL | |
| 40 mM | 0.1081 mL | 0.5404 mL | 1.0809 mL | 2.7022 mL | |
| 50 mM | 0.0865 mL | 0.4324 mL | 0.8647 mL | 2.1618 mL | |
| 60 mM | 0.0721 mL | 0.3603 mL | 0.7206 mL | 1.8015 mL | |
| 80 mM | 0.0540 mL | 0.2702 mL | 0.5404 mL | 1.3511 mL | |
| 100 mM | 0.0432 mL | 0.2162 mL | 0.4324 mL | 1.0809 mL |
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