Regrelor
Regrelor (INS50589 (free acid)) is a selective, reversible, and competitive P2Y12 receptor antagonist and an adenosine 5′-monophosphate derivative. Regrelor inhibits ADP (HY-W010918)-induced aggregation of human washed platelets with an IC50 of 0.016 μM. Intravenous infusion of Regrelor rapidly and dose-dependently inhibits ADP-induced platelet function, and platelet function gradually recovers after cessation of infusion. Regrelor can be used for research on P2Y12-mediated platelet function and cardiovascular regulation.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 787548-03-2
- 分子式: C22H25N6O8P
- 分子量:532.44
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
- プロトコル
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
P2Y Receptor アイソフォーム固有の製品をすべて表示
More
生物活性
製品説明
IC50 & Target
[2]|
P2Y12 Receptor |
体外実験
Regrelor inhibits platelet aggregation in human whole blood with a potency of 0.180 μM[1].
Regrelor inhibits platelet aggregation in human platelet-rich plasma (PRP) with a potency of 0.760 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
CAS 番号 787548-03-2
-
分子量 532.44
-
分子式 C22H25N6O8P
-
SMILES
OP(OC[C@H]1O[C@@H](N(C=N2)C3=C2C(NC(NCC)=O)=NC=N3)[C@H]4[C@@H]1O[C@H](/C=C/C5=CC=CC=C5)O4)(O)=O
-
別名
INS50589 free acid
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Regrelor 関連分類
HY-189107 関連分類
Powered by Bioz