RIOK2-IN-2
RIOK2-IN-2 (8) is a RIOK2 inhibitor, with IC50 values of 3.02 μM and 5.34 μM in MKN-1 and MOLT4 cells, respectively.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2648987-17-9
- 分子式: C27H23F3N6O2
- 分子量:520.51
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
|
RIOK2 |
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| MKN-1 | IC50 |
1.05 μM
Compound: 9
|
Antiproliferative activity against human MKN-1 cells assessed as inhibition of cell proliferation by CCK8 assay
Antiproliferative activity against human MKN-1 cells assessed as inhibition of cell proliferation by CCK8 assay
|
[PMID: 37859717] |
| MOLT-4 | IC50 |
1.57 μM
Compound: 9
|
Antiproliferative activity against human MOLT-4 cells assessed as inhibition of cell proliferation by CCK8 assay
Antiproliferative activity against human MOLT-4 cells assessed as inhibition of cell proliferation by CCK8 assay
|
[PMID: 37859717] |
| U-87MG ATCC | IC50 |
1.25 μM
Compound: 9
|
Antiproliferative activity against human U-87 MG cells assessed as inhibition of cell proliferation by CCK8 assay
Antiproliferative activity against human U-87 MG cells assessed as inhibition of cell proliferation by CCK8 assay
|
[PMID: 37859717] |
化学情報
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CAS 番号 2648987-17-9
-
分子量 520.51
-
分子式 C27H23F3N6O2
-
SMILES
O=C1NC2=CC=C(C3=CC=C(OC)N=C3)C=C2C4=C1C=NN4C5=CC=C(N6CCNCC6)C(C(F)(F)F)=C5
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輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)