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United States

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製品番号: HY-P4096B

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scHAP-1

scHAP-1 is a scrambled HAP-1 peptide, and HAP-1 is a synovial homing peptide. After amino acid sequence scrambling, scHAP-1 still specifically binds to human and rabbit fibroblast-like synoviocytes (FLS), while showing extremely weak binding to human umbilical vein endothelial cells, which proves that it remains an effective FLS-targeting ligand. scHAP-1 can be used in studies related to rheumatoid arthritis.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

分子式: C₆₀H₉₀N₁₈O₁₇
分子量:1335.47

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

scHAP-1 構造式

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

体内実験

Animal Model:

Wistar rats (female; adjuvant-induced arthritis model)^[1]
Dosage:

0.5 mg drug/0.5 ml/250 g rat/day
Administration:

i.v.; two consecutive days
Result:

Showed a 9-fold increase in fluorescence signal in arthritic joints compared to unaffected joints in the same animals at 3 hours post-injection.

Related Protocols :

化学情報

分子量 1335.47
分子式 C₆₀H₉₀N₁₈O₁₇
配列

Ala-Leu-Ser-Gln-Ala-Phe-Arg-His-Ala-Phe-Thr-Ser
シーケンスの短縮

ALSQAFRHAFTS
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (257 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Vanniasinghe AS, et al. Targeting fibroblast-like synovial cells at sites of inflammation with peptide targeted liposomes results in inhibition of experimental arthritis. Clin Immunol. 2014;151(1):43-54. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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