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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
35 Results for "
complement component C5
" in MedChemExpress (MCE) Product Catalog:
Products (35)
35 Results for "complement component C5" in MCE Product Catalog:
7
7 Publications Verification
製品番号: HY-P7695
純度: ≥ 95%, as determined by reducing SDS-PAGE.
別名: C5; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 4; complement C5; C5a Anaphylatoxin; CPAMD4; Prepro-C5; complement component 5; Anaphylatoxin C5a Analog; C5a; ECLZB; C5b; C5D
Species:
Mouse
Source:
E. coli
1
1 Cited Publications
製品番号: HY-P700862
純度: ≥ 95%, as determined by Bis-Tris PAGE.
別名: C5; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 4; complement C5; C5a Anaphylatoxin; CPAMD4; Prepro-C5; complement component 5; Anaphylatoxin C5a Analog; C5a; ECLZB; C5b; C5D
Species:
Human
Source:
HEK293
1
1 Cited Publications
製品番号: HY-P7864
純度: ≥ 95%, as determined by reducing SDS-PAGE.
別名: C5; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 4; complement C5; C5a Anaphylatoxin; CPAMD4; Prepro-C5; complement component 5; Anaphylatoxin C5a Analog; C5a; ECLZB; C5b; C5D
Species:
Human
Source:
E. coli
1
1 Cited Publications
製品番号: HY-P81185
別名: C5; C6; C7; C8; C9; complement component 5; complement component 6; complement component 7; complement component 8; complement component 9; MAC; Membrane attack complex; TCC; Terminal complement complex.
1
製品番号: HY-P3502
CAS 番号: 1841136-73-9
別名: RA101495; RA3193
Target:
研究分野:
製品番号: HY-NP004
別名: CVF
製品番号: HY-145720
CAS 番号: 1639264-46-2
別名: ALN-CC5
研究分野:
Cemdisiran (ALN-CC5) is an N-acetylgalactosamine-conjugated RNAi agent and also a complement component C5 inhibitor. Cemdisiran targets C5 mRNA, cleaves C5 mRNA via the endogenous RNA interference pathway, and inhibits the production of C5 protein in the liver. Cemdisiran exerts a dose-dependent inhibitory effect on total C5 concentrations in cynomolgus monkeys. When used in combination with Pozelimab (HY-P99786) in cynomolgus monkeys, Cemdisiran achieves a more sustained and complete inhibitory effect on complement activity. Cemdisiran can be used in the research of paroxysmal nocturnal hemoglobinuria and other complement-mediated diseases .
製品番号: HY-148457
CAS 番号: 1613641-69-2
別名: Izervay
Avacincaptad pegol (Izervay) is a selective inhibitor targeting complement component C5, and is a pegylated ribonucleic acid aptamer. Avacincaptad pegol inhibits the cleavage of C5 into pro-inflammatory C5a and C5b, which forms the membrane attack complex (C5b-9), thereby reducing inflammatory cell recruitment and retinal cell damage. Avacincaptad pegol can slow the growth of geographic atrophy (GA) lesions and reduce the risk of persistent vision loss. Avacincaptad pegol can be used in research of geographic atrophy associated with age-related macular degeneration (AMD) and has been approved by the FDA .
製品番号: HY-145720A
純度: 96.02%
別名: ALN-CC5 sodium
Cemdisiran sodium (ALN-CC5 sodium) is an N-acetylgalactosamine-conjugated RNAi agent and also a complement component C5 inhibitor. Cemdisiran sodium targets C5 mRNA, cleaves C5 mRNA via the endogenous RNA interference pathway, and inhibits the production of C5 protein in the liver. Cemdisiran sodium exerts a dose-dependent inhibitory effect on total C5 concentrations in cynomolgus monkeys. When used in combination with Pozelimab (HY-P99786) in cynomolgus monkeys, Cemdisiran sodium achieves a more sustained and complete inhibitory effect on complement activity. Cemdisiran sodium can be used in the research of paroxysmal nocturnal hemoglobinuria and other complement-mediated diseases .
製品番号: HY-P3502B
Target:
研究分野:
Zilucoplan (PEG2) is a Zilucoplan (HY-P3502) derivative, where the linker section replaces PEG24 by PEG2. Zilucoplan is a potent complement component 5 (C5) inhibitor .
製品番号: HY-P3502A
別名: RA101495 TFA; RA3193 TFA
Target:
研究分野:
製品番号: HY-P99886
CAS 番号: 219685-93-5
別名: h5G1. 1-SC
Target:
製品番号: HY-P704326
純度: ≥ 95%, as determined by reducing SDS-PAGE.
別名: C5; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 4; complement C5; C5a Anaphylatoxin; CPAMD4; Prepro-C5; complement component 5; Anaphylatoxin C5a Analog; C5a; ECLZB; C5b; C5D
Species:
Mouse
Source:
HEK293
製品番号: HY-P705144
純度: ≥ 95%, as determined by reducing SDS-PAGE.
別名: C5; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 4; complement C5; C5a Anaphylatoxin; CPAMD4; Prepro-C5; complement component 5; Anaphylatoxin C5a Analog; C5a; ECLZB; C5b; C5D
Species:
Human
Source:
HEK293
製品番号: HY-P704336
純度: ≥ 90%, as determined by reducing SDS-PAGE.
別名: C5; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 4; complement C5; C5a Anaphylatoxin; CPAMD4; Prepro-C5; complement component 5; Anaphylatoxin C5a Analog; C5a; ECLZB; C5b; C5D
Species:
Human
Source:
HEK293
製品番号: HY-P705192
純度: ≥ 95%, as determined by reducing SDS-PAGE.
別名: C5; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 4; complement C5; C5a Anaphylatoxin; CPAMD4; Prepro-C5; complement component 5; Anaphylatoxin C5a Analog; C5a; ECLZB; C5b; C5D
Species:
Cynomolgus
Source:
HEK293
製品番号: HY-P705283
純度: ≥ 95%, as determined by reducing SDS-PAGE.
別名: C5; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 4; complement C5; C5a Anaphylatoxin; CPAMD4; Prepro-C5; complement component 5; Anaphylatoxin C5a Analog; C5a; ECLZB; C5b; C5D
Species:
Rat
Source:
HEK293
製品番号: HY-P704546
純度: ≥ 90%, as determined by SDS-PAGE.
別名: C5; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 4; complement C5; C5a Anaphylatoxin; CPAMD4; Prepro-C5; complement component 5; Anaphylatoxin C5a Analog; C5a; ECLZB; C5b; C5D
Species:
Human
Source:
HEK293
製品番号: HY-P704547
純度: ≥ 95%, as determined by reducing SDS-PAGE.
別名: C5; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 4; complement C5; C5a Anaphylatoxin; CPAMD4; Prepro-C5; complement component 5; Anaphylatoxin C5a Analog; C5a; ECLZB; C5b; C5D
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
