Sulconazole
Based on 1 publication(s) in Google Scholar
Sulconazole is a potent antifungal agent in the imidazole class. Sulconazole blocks the NF-κB/IL-8 signaling pathway and CSC (Cancer stem cells) formation. Sulconazole inhibits tumor growth, and can be used for breast cancer research.
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- CAS 番号: 61318-90-9
- 分子式: C18H15Cl3N2S
- 分子量:397.75
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
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- 純度とドキュメンテーション
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MedChemExpress（MCE）の使用を引用している文献 Sulconazole
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生物活性
製品説明
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK-293T | IC50 |
10.1 μM
Compound: Sulconazole
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Inhibition of mouse Ido2 transfected in HEK293T cells using L-tryptophan as substrate assessed as kynurenine formation after 45 mins by spectrophotometric analysis
Inhibition of mouse Ido2 transfected in HEK293T cells using L-tryptophan as substrate assessed as kynurenine formation after 45 mins by spectrophotometric analysis
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[PMID: 23122865] |
| HEK-293T | IC50 |
29.3 μM
Compound: Sulconazole
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Inhibition of mouse Ido1 transfected in HEK293T cells using L-tryptophan as substrate assessed as kynurenine formation after 45 mins by spectrophotometric analysis
Inhibition of mouse Ido1 transfected in HEK293T cells using L-tryptophan as substrate assessed as kynurenine formation after 45 mins by spectrophotometric analysis
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[PMID: 23122865] |
化学情報
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CAS 番号 61318-90-9
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分子量 397.75
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分子式 C18H15Cl3N2S
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SMILES
ClC1=CC=C(C(SCC2=CC=C(Cl)C=C2)CN3C=CN=C3)C(Cl)=C1
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別名
(±)-Sulconazole
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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FASEB J
Sulconazole Suppresses Colorectal Cancer Immune Evasion by Inhibiting Glycolysis to Upregulate OVOL2 PARylation and Induce PANoptosis. [Abstract]2026 Jun 15;40(11):e71948. PMID: 42252920
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Sulconazole 関連分類
HY-B1460B 関連分類
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