country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

製品番号: HY-W075176

Copy Link Print Information

Transfluthrin

Transfluthrin is an insecticide with extremely low acute toxicity to vertebrates. Transfluthrin acts as a mosquito repellent, exerts mosquito control effects via electric heating fumigators, and is widely used in studies related to malaria, bancroftian filariasis and mosquito-borne infectious diseases. Transfluthrin may also induce adverse reactions such as pulmonary sensory irritation, sensitization, genotoxicity and respiratory depression, and can increase the concentrations and activities of CYP2E1 and CYP3A2 in rat brains. Transfluthrin can be removed from wastewater through biodegradation and activated sludge adsorption, and can be degraded by microorganisms such as Azovibrio and Tauera.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 118712-89-3
分子式: C₁₅H₁₂Cl₂F₄O₂
分子量:371.15

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

Transfluthrin 構造式

CAS 番号: 118712-89-3

容量

価格（税別）

在庫状況

数量

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

体外実験

Transfluthrin (0.015-5 mg per plate; 60 min/20 min pre-incubation, 48-72 h plate incubation) is non-genotoxic in bacterial reverse mutation assays for reference transfluthrin (TFL-R), while two generic transfluthrin samples (TFL-GVI, TFL-GVIII) induce dose-dependent base-pair substitutions in Salmonella typhimurium TA100 without metabolic activation^[1].
Transfluthrin is genotoxic to human nasal mucosal epithelial cells of the inferior and middle nasal conchae^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

体内実験

Transfluthrin (10×10⁶ normal usage rate; inhalation; repeated; 2 weeks) causes no measurable toxic effects in rats, classifying the products as hazard class 4^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

White outbred male (220-250 g)^[3]
Dosage:

10x normal usage rate
Administration:

Inhalation; repeated; 2 weeks
Result:

Detected no changes in nervous system, respiratory system, or liver function parameters.
Classified products as hazard class 4.

臨床実験

NCT Number	Sponsor	Condition	Start Date	Phase A549
NCT01329991	Plexxikon\|		2011-05	PHASE1

化学情報

CAS 番号 118712-89-3
分子量 371.15
分子式 C₁₅H₁₂Cl₂F₄O₂
SMILES

O=C(OCC1=C(C(F)=CC(F)=C1F)F)[C@H]2C(C)([C@@H]2/C=C(Cl)\Cl)C
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (272 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Pauluhn J, Ozaki K. Transfluthrin: Comparative efficacy and toxicity of reference and generic versions[J]. Regulatory Toxicology and Pharmacology, 2015, 71(1): 78-92.

[2]. Pates H V, et al. Personal protection against mosquitoes in Dar es Salaam, Tanzania, by using a kerosene oil lamp to vaporize transfluthrin[J]. Medical and Veterinary Entomology, 2002, 16(3): 277-284.

[3]. Прохоров Н И, Ходыкина Т М, Виноградова А И, et al. Оценка безопасности бытовых инсектицидных электрофумигирующих средств на основе трансфлутрина и праллетрина[J]. Гигиена и санитария, 2019, 98(4): 374-379.

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

お問い合わせ在庫あり

Amount: USD 0.00

生物活性
- 製品説明
- 体外実験
- 体内実験
- 臨床実験
化学情報
純度とドキュメンテーション
参考文献

製品名:
製品番号:
数量:
日本の代理先をお選びください:

製品名:
CAS 番号:
生物種:
純度:
数量:

Transfluthrin

High-Throughput Bioactive Compound Library

生物活性

化学情報

純度とドキュメンテーション

参考文献

Calculators

Help & FAQs

Transfluthrin 関連分類

HY-W075176 関連分類