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製品番号: HY-15414AS

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Vortioxetine-d₈ hydrobromide

Name: Vortioxetine-d8 hydrobromide
Brand: MedChemExpress
SKU: HY-15414AS
Price: 398.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(別名: Lu AA21004-d8 hydrobromide)

カスタマーレビュー

Based on 1 Customer Validation

Vortioxetine-d₈ (Lu AA 21004-d₈) hydrobromide is the deuterated form of Vortioxetine. Vortioxetine (Lu AA 21004) is an antagonist of 5-HT_3A and 5-HT₇ receptors (K_i: 3.7 nM, 19 nM) and an inhibitor of 5-hydroxytryptamine transporter (SERT) (K_i: 1.6 nM), as well as a 5-HT_1A agonist and a partial 5-HT_1B agonist (K_i: 15 nM, 33 nM).

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

分子式: C₁₈H₁₅D₈BrN₂S

分子量:387.41

保管条件:

4°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Data Sheet (274 KB)

SDS

COA

Vortioxetine-d₈ hydrobromide 構造式

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This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

Data Download

Data Sheet (274 KB)

SDS

COA

取扱説明書 (2659 KB)

Other Forms of Vortioxetine-d₈ hydrobromide:

Vortioxetine hydrobromide
在庫あり

Vortioxetine-d₈
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To place orders, for customer services and technical support, please contact:

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最寄りの代理店をお探しください Your local distributor: Hycultec GmbHHycultec

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参考文献

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

5-HT Receptor アイソフォーム固有の製品をすべて表示
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5-HT Receptor

5-HT₁ Receptor

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5-HT₄ Receptor

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5-HT₆ Receptor

5-HT₇ Receptor

生物活性

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純度とドキュメンテーション

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関連分類

Bioz

生物活性

製品説明

Vortioxetine-d₈ (Lu AA 21004-d₈) hydrobromide is the deuterated form of Vortioxetine. Vortioxetine (Lu AA 21004) is an antagonist of 5-HT_3A and 5-HT₇ receptors (K_i: 3.7 nM, 19 nM) and an inhibitor of 5-hydroxytryptamine transporter (SERT) (K_i: 1.6 nM), as well as a 5-HT_1A agonist and a partial 5-HT_1B agonist (K_i: 15 nM, 33 nM)^[1].

IC₅₀ & Target

5-HT_1A Receptor

5-HT_1B Receptor

5-HT_3A Receptor

5-HT₇ Receptor

5-HT Receptor アイソフォーム固有の製品をすべて表示 :

5-HT Receptor

5-HT₁ Receptor

5-HT₂ Receptor

5-HT₃ Receptor

5-HT₄ Receptor

5-HT₅ Receptor

5-HT₆ Receptor

5-HT₇ Receptor

アプリケーション

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

化学情報

非標識Cas 960203-27-4

性状 Solid

分子量 387.41

分子式 C₁₈H₁₅D₈BrN₂S

Color White to off-white

SMILES

CC1=CC=C(SC2=CC=CC=C2N3C([2H])([2H])C([2H])([2H])NC([2H])([2H])C3([2H])[2H])C(C)=C1.[H]Br

別名

Lu AA21004-d8 hydrobromide

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

4°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (274 KB)

SDS (251 KB)

English - EN (251 KB)

Français - FR (251 KB)

Deutsch - DE (251 KB)

Norwegian - NO (251 KB)

Español - ES (251 KB)

Swedish - SV (251 KB)

Italian - IT (251 KB)

Korean - KR (251 KB)

Portuguese - PT (251 KB)

COA (2659 KB)

元素分析報告書 (2659 KB)

HNMR (2659 KB)

CNMR (2659 KB)

RP-HPLC (2659 KB)

NP-HPLC (2659 KB)

MS (2659 KB)

LCMS (2659 KB)

IR (2659 KB)

GC (2659 KB)

OR (2659 KB)

SDS-PAGE (2659 KB)

SEC-HPLC (2659 KB)

Other Report (2659 KB)

取扱説明書 (2659 KB)

参考文献

[1]. Bang-Andersen B, et al. Discovery of 1-[2-(2,4-dimethylphenylsulfanyl)phenyl]piperazine (Lu AA21004): a novel multimodal compound for the treatment of major depressive disorder. J Med Chem. 2011 May 12;54(9):3206-21. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

=
濃度濃度

×
体積体積

×
分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

×

体積 _(開始) 体積 _(開始)

=

濃度 _(終了) 濃度 _(終了)

×

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Vortioxetine-d₈ hydrobromide 関連分類

HY-15414AS 関連分類

Others GPCR/G Protein Neuronal Signaling

Isotope-Labeled Compounds 5-HT Receptor Serotonin Transporter

疾患領域

Neurological, Eye or Ear Disease

同位体標識化合物

Hot Research Area Internal Standard for Clinical Mass Spectrometry Isotope-Labeled Inhibitors Deuterium (²H, D)

Stable Isotope-Labeled Inhibitors Stable isotope-labeled inhibitors for use in in vivo cell experiments Therapeutic Drug Monitoring: TDM

Neurological Disease

Bioz

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Keywords

Vortioxetine-d₈
Lu AA21004-d8
Isotope-Labeled Compounds
5-HT Receptor
Serotonin Transporter
Inhibitor
inhibitor
inhibit

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Vortioxetine-d8 hydrobromide

5-HT Receptor アイソフォーム固有の製品をすべて表示

生物活性

製品説明

IC50 & Target

アプリケーション

化学情報

純度とドキュメンテーション

参考文献

Calculators

Help & FAQs

Vortioxetine-d8 hydrobromide 関連分類

HY-15414AS 関連分類

Bioz

Keywords

最近チェックした製品

Vortioxetine-d₈ hydrobromide

IC₅₀ & Target

Vortioxetine-d₈ hydrobromide 関連分類