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Cat. No.: HY-173198

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Kaiso-IN-1

Kaiso-IN-1 (Compound 20) is a Kaiso inhibitor with an IC₅₀ of 0.34 μM against A549 cells. Kaiso-IN-1 can be used in research related to lung cancer.

For research use only. We do not sell to patients.

Formula: C₂₄H₂₅NO₅
Molecular Weight:407.46

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

Kaiso-IN-1 Chemical Structure

Price

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Kaiso-IN-1 (Compound 20) is a Kaiso inhibitor with an IC₅₀ of 0.34 μM against A549 cells. Kaiso-IN-1 can be used in research related to lung cancer.

Chemical Information

Molecular Weight 407.46
Formula C₂₄H₂₅NO₅
SMILES

NC(CC(OCC)=O)C1=CC=C(OC)C(OC2=CC=C(C3=CC=C(O)C=C3)C=C2)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocols

All Cell Biology

Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Lin T, et al. Design, synthesis and evaluation of diphenyl ether-based kaiso inhibitors with enhanced potency. Bioorg Med Chem Lett. 2025 Jun 1;121:130158. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Minimum order quantity

100 mg

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