Keap1-Nrf2-IN-18
Keap1-Nrf2-IN-18 (Compound 22) is an orally active Keap1-Nrf2 protein-protein interaction (PPI) inhibitor with good pharmacokinetics (PK) profiles and more potent in vivo activities in rats. Keap1-Nrf2-IN-18 has the strongest inhibitory activity in structure−activity relationship (SAR) study (KD = 0.0029 μM).
For research use only. We do not sell to patients.
- Formula: C27H29FN2O4
- Molecular Weight:464.53
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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Molecular Weight 464.53
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Formula C27H29FN2O4
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SMILES
CC1=CC=C([C@@H](NC([C@H](C2=CC=C(CC3=NC=CC=C3OCC)C=C2)F)=O)[C@@H](C)C(O)=O)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)