KFA-027
KFA-027 is a HIV-1 inhibitor, with an IC50 of 0.398 nM. KFA-027 inhibits capsid-dependent early steps (reverse transcription, nuclear import, integration) and late-stage aberrant capsid assembly in the HIV-1 replication cycle. KFA-027 can be used for the study of multidrug-resistant HIV-1 infections.
For research use only. We do not sell to patients.
- Formula: C39H34ClF8N7O5S2
- Molecular Weight:932.30
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Chemical Information
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Molecular Weight 932.30
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Formula C39H34ClF8N7O5S2
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SMILES
CC(C#CC1=NC([C@@H](NC(CN2N=C(C3=C2C(F)([C@H]4[C@@H]3C4)F)C(F)(F)F)=O)CC5=CC=CC=C5)=C(C=C1)C6=C7C(C(NS(C)(=O)=O)=NN7CC(F)(F)F)=C(C=C6)Cl)(S(C)(=O)=O)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
KFA-027 Related Classifications
HY-178741 Related Classifications
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