PTER - phosphotriesterase related Gene

Also Known as HPHRP; RPR-1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 9317

About PTER

Cytogenetic location: 10p13 Genomic coordinates (GRCh38): 10:16,437,010-16,519,020 (from NCBI)

This gene has 5 transcripts (splice variants) and 205 orthologues. Ubiquitous expression in kidney (RPKM 11.0), brain (RPKM 10.8) and 25 other tissues.

Summary

Predicted to enable hydrolase activity, acting on ester bonds and zinc ion binding activity. Involved in epithelial cell differentiation. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

PTER Products (5)

mRNA Protein Name
NM_001001484.3 NP_001001484.1 phosphotriesterase-related protein isoform 1
NM_001261836.2 NP_001248765.1 phosphotriesterase-related protein isoform 1
NM_001261837.2 NP_001248766.1 phosphotriesterase-related protein isoform 2
NM_001261838.2 NP_001248767.1 phosphotriesterase-related protein isoform 3
NM_030664.5 NP_109589.2 phosphotriesterase-related protein isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
Biological Process GO Annotation Evidence References Source
involved in epithelial cell differentiation IEP
IEP: Inferred from expression pattern
21492153 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PTER Protein Structure

PTE

PTE: Phosphotriesterase family (15 - 347)

  • 0
  • 100
  • 200
  • 300
  • 349 a.a.
Protein Preferred Names Protein Names

phosphotriesterase-related protein

  • parathion hydrolase-related protein

PTER Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
PTER Q96BW5 GSC2 Homo sapiens O15499
Y2H Prey Pooling
32296183
Intra
PTER Q96BW5 GSC2 Homo sapiens O15499
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Mucinous Bronchioloalveolar Adenocarcinoma

  • Bronchiolo-Alveolar Carcinoma, Mucinous
Dihydropyrimidinase Deficiency

  • Dihydropyrimidinuria

  • Dpys Deficiency

  • Dph Deficiency

  • DPYSD

  • Dihydrouracil Amidohydrolase Deficiency

  • Dihydropyrimidinuria Due To Dpys Deficiency
Bjornstad Syndrome

  • BJS

  • Pili Torti And Nerve Deafness

  • Ptd

  • Pili Torti-Deafness Syndrome

  • Deafness-Pili Torti-Hypogonadism Syndrome

  • Deafness And Pili Torti, Bjornstad Type

  • Pili Torti-Sensorineural Hearing Loss

  • Björnstad Syndrome

  • Ptnd

  • Hearing Loss-Pili Torti-Hypogonadism Syndrome

  • Bjoernstad Syndrome
Secondary Syphilis

  • Syphilis, Secondary

  • Secondary Syphilis Of Viscera Or Bone
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-157126 Pterostilbene-isothiocyanate Inhibitor / Unkown
HY-185341 PTERi Inhibitor 98.04% Unkown
HY-RS11366 PTER Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18495 Pter Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24977 Pter Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus PTER VGNC VGNC:69140
Rattus norvegicus PTER RGD RGD:61313
Mus musculus PTER MGD MGI:107372
Canis familiaris PTER VGNC VGNC:45139
Macaca mulatta PTER VGNC VGNC:76466
Bos taurus PTER VGNC VGNC:33497
Others PTER NCBI