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Cat. No.: HY-N3341

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Macrocarpal H

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Macrocarpal H is a natural compound that can be isolated from the Leaves of Eucalyptus globulus. Macrocarpal H exhibits antibacterial activity against Gram-positive cariogenic bacteria and Gram-negative periodontopathic bacteria. Macrocarpal H inhibits adherent water-insoluble glucan synthesis via glucosyltransferase. Macrocarpal H can be used for the research of caries, periodontal disease, dental caries, periodontal disorders.

For research use only. We do not sell to patients.

Purity: 73.0%
CAS No.: 179388-53-5
Formula: C₂₈H₄₀O₆
Molecular Weight:472.61

Storage:

-20°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Macrocarpal H Chemical Structure

CAS No.: 179388-53-5

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

In Vitro

Macrocarpal H (compound 7) (24-48 h) potently inhibits the growth of cariogenic bacteria including S. mutans Ingbritt, S. mutans LA7, S. sobrinus 6715, S. sobrinus B13, and A. viscosus 15987, and periodontopathic bacteria including P. gingivalis 33277, P. melaninogenica 25845, P. intermedia 25611, and C. ochracea 33596, with MIC values ranging from 0.39 to 3.13 µg/mL, and shows weaker activity against F. nucleatum 25586 with an MIC of 6.25 µg/mL^[2].
Macrocarpal H (1-100 µg/mL; 16 h) strongly inhibits glucosyltransferase activity from S. sobrinus 6715, reducing adherent water-insoluble glucan synthesis by 97.6% at 100 µg/mL and 64.0% at 10 µg/mL^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 179388-53-5
Appearance Solid
Molecular Weight 472.61
Formula C₂₈H₄₀O₆
Color Light yellow to yellow
SMILES

CC(C)C[C@H](C1=C(C(C=O)=C(O)C(C=O)=C1O)O)[C@@]2([H])[C@]3([C@@](C(CC2)=C)([H])C[C@H](C(C)(O)C)CC3)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (277 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Kenji OSAWA, et al. Configuraitonal and Conformational Analysis of Macrocarpals H, I, and J from Eucalyptus globulus. Chemical and Pharmaceutical Bulletin. 1997, Volume 45, Issue 7, Pages 1216-1217.

[2]. Osawa K, et al. Macrocarpals H, I, and J from the Leaves of Eucalyptus globulus. J Nat Prod. 1996 Sep;59(9):823-7. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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