2,6-Dihydroxyxanthone
2,6-Dihydroxyxanthone is a natural xanthone.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 838-11-9
- 화학식: C13H8O4
- 분자량:228.20
-
보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
제품 설명
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| COLO 320 | IC50 |
31.5 μM
Compound: 3-20
|
Antiproliferative activity against human COLO320 cells after 48 hrs by CCK8 assay
Antiproliferative activity against human COLO320 cells after 48 hrs by CCK8 assay
|
[PMID: 28376372] |
| HepG2 | IC50 |
52.2 μM
Compound: 3-20
|
Antiproliferative activity against human HepG2 cells after 48 hrs by CCK8 assay
Antiproliferative activity against human HepG2 cells after 48 hrs by CCK8 assay
|
[PMID: 28376372] |
| HSC-T6 | IC50 |
>30 μM
Compound: 7
|
Antiproliferative activity against rat HSC-T6 cells assessed as reduction in cell viability
Antiproliferative activity against rat HSC-T6 cells assessed as reduction in cell viability
|
[PMID: 25322455] |
| K562 | IC50 |
88.9 μM
Compound: 3-20
|
Antiproliferative activity against human K562 cells after 48 hrs by CCK8 assay
Antiproliferative activity against human K562 cells after 48 hrs by CCK8 assay
|
[PMID: 28376372] |
| MCF7 | IC50 |
92.4 μM
Compound: 3-20
|
Antiproliferative activity against human MCF7 cells after 48 hrs by CCK8 assay
Antiproliferative activity against human MCF7 cells after 48 hrs by CCK8 assay
|
[PMID: 28376372] |
| MDA-MB-231 | IC50 |
32.4 μM
Compound: 3-20
|
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by CCK8 assay
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by CCK8 assay
|
[PMID: 28376372] |
In Vitro
2,6-Dihydroxyxanthone (Compound 11) exhibits preferential cytotoxicity against PANC-1 human pancreatic cancer cells in nutrient-deprived medium (PC50 = 45.2 μM)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
-
CAS No. 838-11-9
-
분자량 228.20
-
화학식 C13H8O4
-
SMILES
O=C1C2=CC=C(C=C2OC3=CC=C(C=C13)O)O
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Initial Source
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선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)