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Cat. No.: HY-106120

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Adolezesin

Name: Adolezesin
Brand: MedChemExpress
SKU: HY-106120
Price: 900.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: Adozelesin; U 73975)

고객리뷰

Based on 1 Customer Validation

Adolezesin (U 73975) is an analog of CC-1065. Adolezesin is an antineoplastic agent.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 110314-48-2
화학식: C₃₀H₂₂N₄O₄
분자량:502.52

보관:

-80°C

Data Sheet (269 KB)

Adolezesin Chemical Structure

CAS No.: 110314-48-2

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

Adolezesin (U 73975) is an analog of CC-1065. Adolezesin is an antineoplastic agent^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
HeLa	IC₅₀	0.0364 ng/mL Compound: 5	Concentration required to inhibit the growth of HeLaS3 human uterine cervix carcinoma cells by 50% Concentration required to inhibit the growth of HeLaS3 human uterine cervix carcinoma cells by 50%	[PMID: 10212131]

In Vitro

Adolezesin (U73975; 0-50 pg/mL; 90 min) inhibits ATP contents with IC₅₀s of 0.097, 0.14, 0.36, 0.53 and 1.65 pg/mL against SKUT1B, AN3, AE7, HEC1A and BG1, respectively^[1].
Adolezesin (0-50 pg/mL; 0-168 h) blocks cell cycle at S and G2 phases in SKUT1B cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .

Cell Cycle Analysis^[1]

View Protocol

Cell Line:

SKUT1B
Concentration:

1, 2, 5, 10 and 50 pg/mL
Incubation Time:

0-168 h
Result:

Blocks cell cycle at S and G2 phases at 50 pg/mL in SKUT1B cells.

Chemical Information

CAS No. 110314-48-2
Appearance Solid
분자량 502.52
화학식 C₃₀H₂₂N₄O₄
Color White to light yellow
SMILES

O=C(C1=CC2=CC=CC=C2O1)NC3=CC4=C(NC(C(N5C[C@](C6)([H])[C@]76C8=C(NC=C8C)C(C=C57)=O)=O)=C4)C=C3
Synonyms

Adozelesin; U 73975
선적

Shipping with dry ice.
보관

-80°C

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Nguyen HN, et al. Spectrum of cell-cycle kinetics of alkylating agent adolezesin in gynecological cancer cell lines: correlation with drug-induced cytotoxicity. J Cancer Res Clin Oncol. 1992;118(7):515-22. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

Minimum order quantity

100 mg

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