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Cat. No.: HY-134971

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AE9C90CB

AE9C90CB, muscarinic receptor antagonist, has greater affinity for M3 muscarinic receptors with pK_i of 9.90 and was 20-fold more selective for M3 than for M2 muscarinic receptors.

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CAS No.: 893426-98-7
화학식: C₂₁H₂₅ClN₂O₂
분자량:372.89

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

AE9C90CB Chemical Structure

CAS No.: 893426-98-7

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수량

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

AE9C90CB, muscarinic receptor antagonist, has greater affinity for M3 muscarinic receptors with pK_i of 9.90 and was 20-fold more selective for M3 than for M2 muscarinic receptors^[1].

IC₅₀ & Target^[1]

mAChR1

9.7 (pKi)

mAChR2

8.6 (pKi)

mAChR3

9.9 (pKi)

mAChR4

9.5 (pKi)

mAChR5

9.5 (pKi)

All mAChR Isoforms :

Chemical Information

CAS No. 893426-98-7
분자량 372.89
화학식 C₂₁H₂₅ClN₂O₂
SMILES

[H][C@@]1(CNC2)[C@@]2([H])[C@H]1CN(C)C(C(C3=CC=CC=C3)(C4=CC=CC=C4)O)=O.Cl
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. S Sinha, et al. AE9C90CB: a novel, bladder-selective muscarinic receptor antagonist for the treatment of overactive bladder. Comparative Study Br J Pharmacol. 2010 Jul;160(5):1119-27. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Biological Activity
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- IC₅₀ & Target
Chemical Information
순도&문서
References

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AE9C90CB

All mAChR Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

AE9C90CB Related Classifications

HY-134971 Related Classifications