Apoptosis inducer 21
Apoptosis inducer 21 (Compound 5h) inhibits the proliferation of lung cancer cell H69AR with an IC50 of 1.58 μM. Apoptosis inducer 21 arrests the cell cycle at G0/G1 phase, induces apoptosis in H69AR.
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- 화학식: C38H29Br2NO6
- 분자량:755.45
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
21.19 μM
Compound: 5h
|
Antiproliferative activity against human A549 cells by SRB assay
Antiproliferative activity against human A549 cells by SRB assay
|
[PMID: 38964518] |
| H69AR | IC50 |
1.58 μM
Compound: 5h
|
Antiproliferative activity against human NCI-H69AR cells by SRB assay
Antiproliferative activity against human NCI-H69AR cells by SRB assay
|
[PMID: 38964518] |
| NCI-H358 | IC50 |
35.82 μM
Compound: 5h
|
Antiproliferative activity against human NCI-H358 cells by SRB assay
Antiproliferative activity against human NCI-H358 cells by SRB assay
|
[PMID: 38964518] |
Chemical Information
-
분자량 755.45
-
화학식 C38H29Br2NO6
-
SMILES
CC1=C(O)C(CC(N2)=C(CC3=C(O)C(C(C4=CC=C(Br)C=C4)=O)=CC(C)=C3O)C5=C2C=CC=C5)=C(O)C(C(C6=CC=C(Br)C=C6)=O)=C1
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선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)