Avosentan (Standard)
Avosentan (Standard) is the analytical standard of Avosentan (HY-15195). This product is intended for research and analytical applications. Avosentan is an orally active endothelin (ETA) receptor antagonist. Avosentan can block the ETA receptor, thereby reducing vascular contraction, and exerting a renal protective effect. Avosentan inhibits vascular contraction caused by ET-1 and alleviates the reduction in retinal and optic nerve head blood flow induced by it, lowering intraocular pressure in the glaucoma monkey model. Avosentan non-specifically blocks ETB receptors at high doses, inhibiting ETB-mediated diuresis and natriuresis, and may cause fluid retention. Avosentan can be used to reduce proteinuria with diabetic nephropathy, but induces significant fluid overload and congestive heart failure.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity : 98%
- CAS No.: 290815-26-8
- 화학식: C23H21N5O5S
- 분자량:479.51
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- 순도&문서
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Help & FAQs
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HY-15403A
Atrasentan hydrochlorideETA Receptor Antagonist -
HY-A0013
BosentanET-1 Inhibtior -
HY-10088
ZibotentanETA Receptor Antagonist -
HY-15195
AvosentanETA Receptor Antagonist -
HY-15403
AtrasentanEndothelin Receptor Antagonist -
HY-14184
MacitentanETA/ETB Antagonist -
HY-A0013A
Bosentan hydrateET1 Receptor Antagonist -
HY-15894A
BQ-788ETB Receptor Antagonist -
HY-15895
AprocitentanEndothelin Receptor Antagonist -
HY-14184R
Macitentan (Standard)ETA/ETB Antagonist -
HY-13209
Ambrisentan -
HY-12378
BQ-123ETA Receptor Antagonist
Product Information
Information
신청
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 290815-26-8
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분자량 479.51
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화학식 C23H21N5O5S
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SMILES
COC1=C(OC(C(NS(C2=NC=C(C=C2)C)(=O)=O)=NC(C3=CC=NC=C3)=N4)=C4OC)C=CC=C1
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Synonyms
Ro 67-0565 (Standard); SPP-301 (Standard)
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Avosentan (Standard) Related Classifications
HY-15195R Related Classifications
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