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Cat. No.: HY-124826

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BC21

(Synonyms: NSC 109268)

BC21 (NSC 109268) is a β-catenin/Tcf4 inhibitor with an IC₅₀ of 5 μM. BC21 effectively inhibits the binding of β-catenin to Tcf4-derived peptides and suppresses β-catenin/Tcf4-driven reporter gene activity. BC21 can be utilized in cancer research.

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CAS No.: 691005-38-6
화학식: C₃₂H₃₆Cl₂Cu₂N₂O₂
분자량:678.64

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

BC21 Chemical Structure

CAS No.: 691005-38-6

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

Chemical Information

CAS No. 691005-38-6
분자량 678.64
화학식 C₃₂H₃₆Cl₂Cu₂N₂O₂
SMILES

C12=CC=C3C(C=CC=C3)=C1C[N]4(CCCCC4)[Cu+2]5([O-]2)[Cl-][Cu+2]6([N]7(CCCCC7)CC8=C(C=CC=C9)C9=CC=C8[O-]6)[Cl-]5
Synonyms

NSC 109268
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Tian W, et al. Structure-based discovery of a novel inhibitor targeting the β-catenin/Tcf4 interaction. Biochemistry. 2012 Jan 17;51(2):724-31. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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