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Cat. No.: HY-124918

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Cremastranone

Cremastranone is an antiangiogenic homoisoflavone. Cremastranone can inhibit HUVECs cell proliferation, with a GI₅₀ value of 1.5 uM.

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CAS No.: 107585-69-3
화학식: C₁₈H₁₈O₇
분자량:346.33

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

Cremastranone Chemical Structure

CAS No.: 107585-69-3

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

Cremastranone is an antiangiogenic homoisoflavone. Cremastranone can inhibit HUVECs cell proliferation, with a GI₅₀ value of 1.5 uM^[1].

All VEGFR Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
HUVEC	GI₅₀	0.38 μM Compound: 1	Growth inhibition of human HUVEC cells assessed as reduction in cell number after 48 hrs by alamarBlue based fluorescence assay Growth inhibition of human HUVEC cells assessed as reduction in cell number after 48 hrs by alamarBlue based fluorescence assay	[PMID: 26035340]
Y79	GI₅₀	9.8 μM Compound: 1	Growth inhibition of human Y79 cells assessed as reduction in cell number after 48 hrs by alamarBlue based fluorescence assay Growth inhibition of human Y79 cells assessed as reduction in cell number after 48 hrs by alamarBlue based fluorescence assay	[PMID: 26035340]

Chemical Information

CAS No. 107585-69-3
분자량 346.33
화학식 C₁₈H₁₈O₇
SMILES

O=C1C2=C(C(OC)=C(C=C2OCC1CC3=CC=C(C(O)=C3)OC)O)O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Lee B, et al. The first synthesis of the antiangiogenic homoisoflavanone, cremastranone. Org Biomol Chem. 2014 Oct 21;12(39):7673-7. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

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Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

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Cremastranone

All VEGFR Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Cremastranone Related Classifications

HY-124918 Related Classifications