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United States

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Cat. No.: HY-N15595

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Curvulol

Curvulol is an antimicrobial agent with a polyketide structure. Curvulol can be isolated from Taxus baccata ( Chaetosphaeronema achilleae). Curvulol has a significant cytotoxicity against L929 and KB-3-1 cells, and strongly inhibits Staphylococcus aureus biofilm formation with a MIC of 64 μg/mL.

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CAS No.: 15817-76-2
화학식: C₁₀H₁₂O₄
분자량:196.20

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

Curvulol Chemical Structure

CAS No.: 15817-76-2

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

In Vitro

Curvulol (Compound 7) shows an antimicrobial activity against Rhodoturula glutinis DSM 10134, Schizosaccharomyces pombe DSM 70572, Staphylococcus aureus DSM 346 and Bacillus subtilis DSM 10 with a MIC of 33.33 μg/mL^[1].
Curvulol has a significant cytotoxicity with _IC50 s of 5.5 and 7.5  μg/mL for L929 and KB-3-1 cells, respectively^[1].
Curvulol (4-256 μg/mL) strongly inhibits Staphylococcus aureus biofilm formation of 96.18% at 256 μg/mL, and with a MIC of 64 μg/mL^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 15817-76-2
분자량 196.20
화학식 C₁₀H₁₂O₄
SMILES

OC1=C2C(CO[C@H]2C)=CC(OC)=C1O
Structure Classification
- Others
Initial Source
- Microorganisms
Chaetosphaeronema achilleae
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Narmani A, Teponno RB, Helaly SE, Arzanlou M, Stadler M. Cytotoxic, anti-biofilm and antimicrobial polyketides from the plant associated fungus Chaetosphaeronema achilleae. Fitoterapia. 2019 Nov; 139:104390. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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