Cyclo(-Met-Pro)
Based on 1 Customer Validation
Cyclo(-Met-Pro) is a cyclic dipeptide consisting of the amino acids methionine and proline. Cyclo(-Met-Pro) exhibits weak inhibitory activity against the influenza A virus (H3N2) (5 mM, 2.1% inhibition), while cis-cyclo(Leu-Pro) and cis-cyclo(Phe-Pro) shows significant antiviral activity.
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- Purity : 99.80%
- CAS No.: 53049-06-2
- 화학식: C10H16N2O2S
- 분자량:228.31
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보관:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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용액&용해도
- Protocol
- 순도&문서
- References
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Help & FAQs
Biological Activity
제품 설명
Chemical Information
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CAS No. 53049-06-2
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Appearance Solid
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분자량 228.31
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화학식 C10H16N2O2S
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Color White to off-white
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Sequence
Cyclo(Met-Pro)
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Sequence Shortening
Cyclo(MP)
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
용액&용해도
In Vitro:
DMSO : ≥ 100 mg/mL (438.00 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Protocol
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
순도&문서
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Data Sheet (271 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.3800 mL | 21.9000 mL | 43.8001 mL | 109.5002 mL |
| 5 mM | 0.8760 mL | 4.3800 mL | 8.7600 mL | 21.9000 mL | |
| 10 mM | 0.4380 mL | 2.1900 mL | 4.3800 mL | 10.9500 mL | |
| 15 mM | 0.2920 mL | 1.4600 mL | 2.9200 mL | 7.3000 mL | |
| 20 mM | 0.2190 mL | 1.0950 mL | 2.1900 mL | 5.4750 mL | |
| 25 mM | 0.1752 mL | 0.8760 mL | 1.7520 mL | 4.3800 mL | |
| 30 mM | 0.1460 mL | 0.7300 mL | 1.4600 mL | 3.6500 mL | |
| 40 mM | 0.1095 mL | 0.5475 mL | 1.0950 mL | 2.7375 mL | |
| 50 mM | 0.0876 mL | 0.4380 mL | 0.8760 mL | 2.1900 mL | |
| 60 mM | 0.0730 mL | 0.3650 mL | 0.7300 mL | 1.8250 mL | |
| 80 mM | 0.0548 mL | 0.2738 mL | 0.5475 mL | 1.3688 mL | |
| 100 mM | 0.0438 mL | 0.2190 mL | 0.4380 mL | 1.0950 mL |
Cyclo(-Met-Pro) Related Classifications
HY-P1937 Related Classifications
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