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United States

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Cat. No.: HY-W1130442

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DMA4-H228

DMA4-H228 is a highly spleen-targeted, ionizable cationic liposome. DMA4-H228 is used to prepare lipid nanoparticles (LNPs) loaded with mRNA for the delivery of mRNA in vivo.

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CAS No.: 3091917-64-2
화학식: C₅₇H₁₀₆N₄O₁₀
분자량:1007.47

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (275 KB)

DMA4-H228 Chemical Structure

CAS No.: 3091917-64-2

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

DMA4-H228 is a highly spleen-targeted, ionizable cationic liposome. DMA4-H228 is used to prepare lipid nanoparticles (LNPs) loaded with mRNA for the delivery of mRNA in vivo^[1].

Chemical Information

CAS No. 3091917-64-2
분자량 1007.47
화학식 C₅₇H₁₀₆N₄O₁₀
SMILES

O=C(CCC(N(CCCCCCCC)CCCCCCCC)=O)OCCOC(CCN(CCC1N(CCC1)C)CCC(OCCOC(CCC(N(CCCCCCCC)CCCCCCCC)=O)=O)=O)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (275 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Liang X, et al. Dimethylamino-based synthetic lipidoid nanoparticles for selective mRNA delivery to splenic antigen-presenting cells. J Control Release. 2025 Jun 10;382:113737. [Content Brief]

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

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Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

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Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Keywords

MOQ

Minimum order quantity

100 mg

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