Exatecan intermediate 12-d5
Based on 1 Customer Validation
Exatecan intermediate 12-d5 is the deuterium labeled Exatecan intermediate 12 (HY-45171). Exatecan intermediate 12 is an intermediate for the synthesis of ADC toxin Exatecan (HY-13631) and can be used to prepare ADC compounds.
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- Purity : 99.98%
- 화학식: C15H12D5NO6
- 분자량:312.33
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보관:
Store at room temperature, keep dry and cool.
In solvent -80°C, 1 year , -20°C, 6 months
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
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Help & FAQs
Biological Activity
제품 설명
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
신청
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled CAS 110351-93-4
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Appearance Solid
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분자량 312.33
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화학식 C15H12D5NO6
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Color White to off-white
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SMILES
O=C1N2C(C3(CC2)OCCO3)=CC([C@@](C([2H])(C([2H])([2H])[2H])[2H])4O)=C1COC4=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Store at room temperature, keep dry and cool
In solvent -80°C 1 year -20°C 6 months
용액&용해도
In Vitro:
DMSO : ≥ 50 mg/mL (160.09 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (252 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 3.2017 mL | 16.0087 mL | 32.0174 mL | 80.0435 mL |
| 5 mM | 0.6403 mL | 3.2017 mL | 6.4035 mL | 16.0087 mL | |
| 10 mM | 0.3202 mL | 1.6009 mL | 3.2017 mL | 8.0044 mL | |
| 15 mM | 0.2134 mL | 1.0672 mL | 2.1345 mL | 5.3362 mL | |
| 20 mM | 0.1601 mL | 0.8004 mL | 1.6009 mL | 4.0022 mL | |
| 25 mM | 0.1281 mL | 0.6403 mL | 1.2807 mL | 3.2017 mL | |
| 30 mM | 0.1067 mL | 0.5336 mL | 1.0672 mL | 2.6681 mL | |
| 40 mM | 0.0800 mL | 0.4002 mL | 0.8004 mL | 2.0011 mL | |
| 50 mM | 0.0640 mL | 0.3202 mL | 0.6403 mL | 1.6009 mL | |
| 60 mM | 0.0534 mL | 0.2668 mL | 0.5336 mL | 1.3341 mL | |
| 80 mM | 0.0400 mL | 0.2001 mL | 0.4002 mL | 1.0005 mL | |
| 100 mM | 0.0320 mL | 0.1601 mL | 0.3202 mL | 0.8004 mL |
Exatecan intermediate 12-d5 Related Classifications
HY-45171S Related Classifications
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