Clec5a - C-type lectin domain family 5, member a Gene

Also Known as Mdl1; Ly100; MDL-1; Clecsf5

Species: Mus musculus

Gene Type: protein coding
Gene ID: 23845

Summary

Enables virus receptor activity. Involved in several processes, including innate immune response; negative regulation of apoptotic process; and osteoblast development. Acts upstream of or within myeloid cell differentiation and negative regulation of myeloid cell apoptotic process. Located in cell surface. Orthologous to human CLEC5A (C-type lectin domain containing 5A). [provided by Alliance of Genome Resources, Apr 2022]

Clec5a Products (2)

mRNA Protein Name
NM_001038604.1 NP_001033693.1 C-type lectin domain family 5 member A isoform 1
NM_021364.2 NP_067339.1 C-type lectin domain family 5 member A isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
19074552 MGI
enables virus receptor activity IDA
IDA: Inferred from direct assay
18496526 MGI
Biological Process GO Annotation Evidence References Source
involved in innate immune response IDA
IDA: Inferred from direct assay
19074552 MGI
acts upstream of or within myeloid cell differentiation IGI
IGI: Inferred from genetic interaction
24216483 MGI
involved in negative regulation of apoptotic process IDA
IDA: Inferred from direct assay
19074552 MGI
acts upstream of or within negative regulation of myeloid cell apoptotic process IDA
IDA: Inferred from direct assay
19074552 MGI
involved in osteoblast development IDA
IDA: Inferred from direct assay
19251634 MGI
involved in positive regulation of cytokine production IMP
IMP: Inferred from mutant phenotype
18496526 MGI
Cellular Component GO Annotation Evidence References Source
located in cell surface IDA
IDA: Inferred from direct assay
19074552 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

C-type lectin domain family 5 member A

  • C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 5

  • C-type lectin superfamily member 5

  • myeloid DAP12-associating lectin 1

  • type II transmembrane protein MDL-1

Clec5a Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Clec5a Q9R007 Tyrobp Mus musculus O54885
Anti Bait CoIP
19251634
Intra
Clec5a Q9R007 Hcst Mus musculus Q9QUJ0
Anti Bait CoIP
19251634
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant Clec5a Proteins

Cat. No. 상품명 Accession Purity
HY-P77906 CLEC5A/MDL-1 Protein, Mouse (HEK293, Fc) Q9R007-3 (Y26-K190) ≥ 95%, as determined by Bis-Tris PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. 상품명
효과
Purity
Rare Diseases
HY-N2110 Phellopterin 99.94% Unkown
HY-184358 CLEC5A-IN-1 / Unkown
HY-RS02798 CLEC5A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18419 Clec5a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24900 Clec5a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Clec5a NCBI NCBI:23601