human GALP (3-32)
human GALP (3-32) (Galanin-like peptide (3-32)) is a potent galanin receptor agonist with high affinity for both GalR1 (IC50=33 nM) and GalR2 (IC50=15 nM) in a competitive binding study. human GALP (3-32) exhibits the high potency in altering the extracellular acidification rate of SH-SY5Y cells transfected with GalR2 (EC50=360 nM).
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- 화학식: C137H213N43O38S
- 분자량:3102.49
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Neuropeptide Y Receptor Isoforms
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Biological Activity
제품 설명
IC50 & Target
IC50: 15 nM (GalR2 in competitive binding study), 33 nM (GalR1 in competitive binding study)[1]
Chemical Information
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분자량 3102.49
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화학식 C137H213N43O38S
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Synonyms
Galanin-like peptide (3-32)
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Sequence
Ala-His-Arg-Gly-Arg-Gly-Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-Val-Leu-His-Leu-Pro-Gln-Met-Gly-Asp-Gln
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Sequence Shortening
AHRGRGGWTLNSAGYLLGPVLHLPQMGDQ
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocol
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)