KK-92A
KK-92A, a blood-brain barrier penetrated GABAB positive allosteric modulator (PAM), suppresses alcohol self-administration and cue-induced reinstatement of alcohol seeking in rats.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- 화학식: C19H22F3N3O
- 분자량:365.39
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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분자량 365.39
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화학식 C19H22F3N3O
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SMILES
OCC1=NC=C(C2=CC=C(C=C2)C(F)(F)F)C(NC3CCCCCC3)=N1
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Paola Maccioni, et al. The Novel Positive Allosteric Modulator of the GABAB Receptor, KK-92A, Suppresses Alcohol Self-Administration and Cue-Induced Reinstatement of Alcohol Seeking in Rats. Front Cell Dev Biol. 2021 Oct 28:9:727576. [Content Brief]
[2]. Xia Li, et al. KK-92A, a novel GABAB receptor positive allosteric modulator, attenuates nicotine self-administration and cue-induced nicotine seeking in rats. Psychopharmacology (Berl). 2017 May;234(9-10):1633-1644. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)