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Cat. No.: HY-14226

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LIMK-IN-3

LIMK-IN-3 (Compound 33) is a LIMK2 inhibitor (IC₅₀: 1.2 nM). LIMK-IN-3 can be used for glaucoma research.

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CAS No.: 1116570-97-8
화학식: C₂₂H₂₇N₇O₃
분자량:437.49

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

LIMK-IN-3 Chemical Structure

CAS No.: 1116570-97-8

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

LIMK-IN-3 (Compound 33) is a LIMK2 inhibitor (IC₅₀: 1.2 nM). LIMK-IN-3 can be used for glaucoma research^[1].

IC₅₀ & Target^[1]

LIMK2

1.2 nM (IC₅₀)

All LIM Kinase (LIMK) Isoforms :

LIMK1
LIMK2

Cellular Effect

Cell Line	Type	Value	Description	References
Sf9	IC₅₀	1.2 nM Compound: 22j	Inhibition of human recombinant LIMK2 expressed in baculovirus-Sf9 system by scintillation counting Inhibition of human recombinant LIMK2 expressed in baculovirus-Sf9 system by scintillation counting	[PMID: 19831390]

Chemical Information

CAS No. 1116570-97-8
분자량 437.49
화학식 C₂₂H₂₇N₇O₃
SMILES

CC1=CNC2=NC=NC(N3C[C@@H](N(CC3)C(NC4=CC(OC(N(C)C)=O)=CC=C4)=O)C)=C12
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Shen, et al. Theoretical study on the interaction of pyrrolopyrimidine derivatives as LIMK2 inhibitors: insight into structure-based inhibitor design. Molecular bioSystems. 2013, 9(10), 2435–2446. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References

상품명:
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수량:
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LIMK-IN-3

All LIM Kinase (LIMK) Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

LIMK-IN-3 Related Classifications

HY-14226 Related Classifications