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Cat. No.: HY-164705

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Mal-Toxophore

Mal-Toxophore is a drug-linker conjugate for ADC and can be used for ADC synthesis. The payload is a NAMPT inhibitor (HY-164759).

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CAS No.: 2592504-91-9
화학식: C₃₀H₃₃N₇O₅
분자량:571.63

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (263 KB)

Mal-Toxophore Chemical Structure

CAS No.: 2592504-91-9

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Biological Activity

제품 설명

Mal-Toxophore is a drug-linker conjugate for ADC and can be used for ADC synthesis. The payload is a NAMPT inhibitor (HY-164759)^[1].

All Drug-Linker Conjugates for ADC Isoforms :

Chemical Information

CAS No. 2592504-91-9
분자량 571.63
화학식 C₃₀H₃₃N₇O₅
SMILES

O=C1C=CC(N1CC(NCCCCCN2N=C(C(CC2=O)C)C3=CC=C(NC(N4CC5=C(C4)C=CN=C5)=O)C=C3)=O)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (263 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Böhnke N, et al. A Novel NAMPT Inhibitor-Based Antibody-Drug Conjugate Payload Class for Cancer Therapy. Bioconjug Chem. 2022 Jun 15;33(6):1210-1221. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

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Mal-Toxophore

All Drug-Linker Conjugates for ADC Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Mal-Toxophore Related Classifications

HY-164705 Related Classifications