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Cat. No.: HY-189680

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MK-1496

MK-1496 is an orally active and highly selective PLK1 inhibitor. MK-1496 exerts antitumor effects by inducing G2/M phase arrest and apoptosis in tumor cells. MK-1496 can be used in research related to parotid gland carcinoma and small cell lung cancer.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 1037254-47-9
화학식: C₁₄H₂₄N₂O
분자량:236.35

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

MK-1496 Chemical Structure

CAS No.: 1037254-47-9

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
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Biological Activity

제품 설명

IC₅₀ & Target

^[1]

PLK1

All Polo-like Kinase (PLK) Isoforms :

Chemical Information

CAS No. 1037254-47-9
분자량 236.35
화학식 C₁₄H₂₄N₂O
SMILES

CC(C)(C)NC[C@H](C1=CC=C(C=C1)[C@@H](N)C)O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Doi T, et al. A first-in-human phase I dose-escalation study of MK-1496, first-in-class orally available novel PLK1 inhibitor, in patients with advanced solid tumors. J Clin Oncol. 2011;29(15_suppl):3012.

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References

상품명:
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MK-1496

All Polo-like Kinase (PLK) Isoforms

Biological Activity

제품 설명

IC50 & Target

Chemical Information

순도&문서

References

Calculators

Help & FAQs

MK-1496 Related Classifications

HY-189680 Related Classifications

Bioz

Keywords

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