Oosponol
Oosponol is a dopamine beta-hydroxylase inhibitor exhibiting hypotensive effects.Oospongol has strong antifungal activity against many antagonistic fungi.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 146-04-3
- 화학식: C11H8O5
- 분자량:220.18
-
보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
-
Biological Activity
-
Chemical Information
- 순도&문서
- References
-
Help & FAQs
Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Animal Model:Spontaneously hypertensive rats[1]
-
Dosage:6.25 mg/kg, 3.1 mg/kg
-
Administration:Intraperitoneal injection, once.
-
Result:The intraperitoneal injection of 6.25 mg/kg lowered the pressure from 186 mm to 138~112 mm, the intraperitoneal injection of 3.1 mg/kg lowered the pressure from 185 mm to 164~131 mm[1].
-
Animal Model:Spontaneously hypertensive rats[1]
-
Dosage:6.25 mg/kg, 3.1 mg/kg
-
Administration:Intraperitoneal injection, once.
-
Result:The intraperitoneal injection of 6.25 mg/kg lowered the pressure from 186 mm to 138~112 mm, the intraperitoneal injection of 3.1 mg/kg lowered the pressure from 185 mm to 164~131 mm.
Chemical Information
-
CAS No. 146-04-3
-
분자량 220.18
-
화학식 C11H8O5
-
SMILES
O=C1OC=C(C2=C1C(O)=CC=C2)C(CO)=O
-
Structure Classification
-
Initial Source
Gloeophyllum abietinum
-
선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Umezawa H, et al.. Dopamine -hydroxylase inhibitor produced by Gloeophyllum striatum and its identity with oosponol. J Antibiot (Tokyo). 1972 Apr;25(4):239-42. [Content Brief]
[2]. Sonnenbichler J,et al. Influence of the Gloeophyllum metabolite oosponol and some synthetic analogues on protein and RNA synthesis in target cells. Eur J Biochem. 1997 May 15;246(1):45-9. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Powered by Bioz