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United States

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Cat. No.: HY-N12761

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Penpaxilloids A

Penpaxilloids A (Compound 1) is a non-competitive inhibitor of protein tyrosine phosphatase 1B (PTP1B) with an IC₅₀ value of 8.60 μM. Penpaxilloids A can be isolated from the fungus Penicillium sp. ZYX-Z-143. Penpaxilloids A is also an α-glucosidase (α-glucosidase) inhibitor with anti-inflammatory activity.

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화학식: C₃₁H₃₇NO₇
분자량:535.63

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

Penpaxilloids A Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

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Chemical Information

분자량 535.63
화학식 C₃₁H₃₇NO₇
SMILES

O=C(CC1)N2[C@H]1O[C@@]3(C([C@@]([C@](CC[C@@](O[C@@H]4C(C)(O)C)([H])C5=CC4=O)(C)[C@@]5(O)CC6)(C)[C@]6([H])C3)=O)C7=CC=CC=C72
Structure Classification
- Terpenoids
- Diterpenoids
Initial Source
- Marine natural products
- Marine microorganism
Penicillium
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Dai LT, et al. Anti-diabetic and anti-inflammatory indole diterpenes from the marine-derived fungus Penicillium sp. ZYX-Z-143. Bioorg Chem. 2024 Apr;145:107205. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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