Phomopsin D
Phomopsin D, a mycotoxin, is a derivative of Phomopsin A (HY-N6793). Phomopsin A is a cyclic hexapeptide mycotoxin isolated from the fungus Phomopsis leptostomiformis. Phomopsin A is a noncompetitive inhibitor of the binding of radiolabeled vincristine to tubulin.
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- CAS No.: 175617-09-1
- 화학식: C36H47ClN6O12
- 분자량:791.24
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
제품 설명
Chemical Information
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CAS No. 175617-09-1
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분자량 791.24
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화학식 C36H47ClN6O12
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SMILES
O=C(N[C@H]1C(C)=C)[C@@H](NC)[C@@H](O)C2=CC(Cl)=C(O)C(O[C@](C)(CC)[C@@H](C(N3[C@@](C(N/C(C(NC(CC(O)=O)C(O)=O)=O)=C(C)/CC)=O)([H])C=CC3)=O)NC1=O)=C2
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Structure Classification
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Initial Source
Rhizopus oligosporus
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Sogahata K, et al. Biosynthetic Studies of Phomopsins Unveil Posttranslational Installation of Dehydroamino Acids by UstYa Family Proteins. Angew Chem Int Ed Engl. 2021 Dec 1;60(49):25729-25734. [Content Brief]
[2]. Hamel E. Natural products which interact with tubulin in the vinca domain: maytansine, rhizoxin, phomopsin A, dolastatins 10 and 15 and halichondrin B. Pharmacol Ther. 1992;55(1):31-51. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)