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Cat. No.: HY-156458A

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(R)-SR-29065

(R)-SR-29065 is a selective REV-ERBα inhibitor with a IC₅₀ of 10 nM. (R)-SR-29065 is applicable to research related to autoimmune diseases.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 2756883-91-5
화학식: C₂₄H₂₄F₆N₂O₂S
분자량:518.51

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (277 KB)

(R)-SR-29065 Chemical Structure

CAS No.: 2756883-91-5

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

(R)-SR-29065 is a selective REV-ERBα inhibitor with a IC₅₀ of 10 nM. (R)-SR-29065 is applicable to research related to autoimmune diseases^[1].

IC₅₀ & Target

^[1]

REV-ERBα

10 nM (IC₅₀)

In Vitro

(R)-SR-29065 (Compound 2) (2 h) promotes the recruitment of SMRT corepressor peptide to purified human REV-ERBα, with an EC₅₀ of 10 nM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2756883-91-5
분자량 518.51
화학식 C₂₄H₂₄F₆N₂O₂S
SMILES

O=S(N[C@H](C1=CN(CC(C)C)C2=CC(C3=C(C=CC=C3)C(F)(F)F)=CC=C12)C(F)(F)F)(C4CC4)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (277 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. He Y, et al. Structure-Activity Relationship and Biological Investigation of a REV-ERBα-Selective Agonist SR-29065 (34) for Autoimmune Disorders. J Med Chem. 2023;66(21):14815-14823. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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