Regrelor
Regrelor (INS50589 (free acid)) is a selective, reversible, and competitive P2Y12 receptor antagonist and an adenosine 5′-monophosphate derivative. Regrelor inhibits ADP (HY-W010918)-induced aggregation of human washed platelets with an IC50 of 0.016 μM. Intravenous infusion of Regrelor rapidly and dose-dependently inhibits ADP-induced platelet function, and platelet function gradually recovers after cessation of infusion. Regrelor can be used for research on P2Y12-mediated platelet function and cardiovascular regulation.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 787548-03-2
- 화학식: C22H25N6O8P
- 분자량:532.44
-
보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Protocol
- 순도&문서
- References
-
Help & FAQs
All P2Y Receptor Isoforms
More
Biological Activity
제품 설명
IC50 & Target
[2]|
P2Y12 Receptor |
In Vitro
Regrelor inhibits platelet aggregation in human whole blood with a potency of 0.180 μM[1].
Regrelor inhibits platelet aggregation in human platelet-rich plasma (PRP) with a potency of 0.760 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 787548-03-2
-
분자량 532.44
-
화학식 C22H25N6O8P
-
SMILES
OP(OC[C@H]1O[C@@H](N(C=N2)C3=C2C(NC(NCC)=O)=NC=N3)[C@H]4[C@@H]1O[C@H](/C=C/C5=CC=CC=C5)O4)(O)=O
-
Synonyms
INS50589 free acid
-
선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Regrelor Related Classifications
HY-189107 Related Classifications
Powered by Bioz